Standard name Systematic name Name description Description
CUP1-1 YHR053C Metallothionein Metallothionein; binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C; CUP1-1 has a paralog, CUP1-2, that arose from a segmental duplication
Visualize the interactome of CUP1-1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.966 0.989 0.972

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 31900

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CUP1-1 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CRS5 YOR031W Copper-binding metallothionein genetic 3 3 3 Dosage Rescue, Phenotypic Suppression, Phenotypic Enhancement
HSF1 YGL073W Trimeric heat shock transcription factor regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex regulation 2 2 1 chromatin immunoprecipitation evidence, quantitative reverse transcription polymerase chain reaction evidence
RSC2 YLR357W Component of the RSC chromatin remodeling complex regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, quantitative reverse transcription polymerase chain reaction evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 reverse transcription polymerase chain reaction evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
CHA4 YLR098C DNA binding transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways regulation 1 1 1 DNA to cDNA expression microarray evidence
OPI1 YHL020C Transcriptional regulator of a variety of genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MSS11 YMR164C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways regulation 1 1 1 DNA to cDNA expression microarray evidence
CUP2 YGL166W Copper-binding transcription factor regulation 1 1 1 fluorescence in situ hybridization evidence
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
INO80 YGL150C Nucleosome spacing factor regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling regulation 1 1 1 chromatin immunoprecipitation evidence
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Synthetic Growth Defect
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Dosage Rescue
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Synthetic Lethality
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Synthetic Lethality
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Synthetic Growth Defect
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Synthetic Growth Defect
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Synthetic Growth Defect
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Phenotypic Enhancement
HHT1 YBR010W Histone H3 genetic 1 1 1 Dosage Rescue