Standard name Systematic name Name description Description
GYL1 YMR192W Putative GTPase activating protein (GAP) with a role in exocytosis Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; increases in abundance and relocalizes from bud neck to cytoplasm upon DNA replication stress; GYL1 has a paralog, GYP5, that arose from the whole genome duplication
Visualize the interactome of GYL1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.056 0.076 NaN
Budsite 0.056 NaN NaN
Cort. Patches 0.197 0.148 0.113
Cytoplasm 0.685 0.773 0.809
Endosome 0.050 NaN NaN
Cell Periphery NaN NaN 0.055

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GYL1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 14 7 8 Affinity Capture-Western, Far Western, Far Western, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Co-localization, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 13 6 9 Two-hybrid, Protein-peptide, Two-hybrid, Two-hybrid, Protein-peptide, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-Western
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 6 3 6 Two-hybrid, Two-hybrid, PCA, Two-hybrid, Two-hybrid, Affinity Capture-Western
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 3 2 3 Protein-peptide, Two-hybrid, Two-hybrid
YSC84 YHR016C Actin-binding protein physical 3 2 3 Protein-peptide, Two-hybrid, Two-hybrid
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity physical 2 1 2 Two-hybrid, Two-hybrid
PHM8 YER037W Lysophosphatidic acid (LPA) phosphatase, nucleotidase genetic 2 1 2 Negative Genetic, Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 2 2 1 Affinity Capture-Western, PCA
RPL36B YPL249C-A Ribosomal 60S subunit protein L36B physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family physical 2 1 1 PCA, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Positive Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Dosage Lethality
ETP1 YHL010C Protein of unknown function required for growth on ethanol physical 1 1 1 Two-hybrid
ARE1 YCR048W Acyl-CoA:sterol acyltransferase physical 1 1 1 Two-hybrid
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Synthetic Lethality
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members genetic 1 1 1 Synthetic Lethality
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 1 1 1 PCA
YNR065C YNR065C Protein of unknown function physical 1 1 1 PCA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
IKS1 YJL057C Protein kinase of unknown cellular role physical 1 1 1 Reconstituted Complex
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family physical 1 1 1 Two-hybrid
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Two-hybrid
SGM1 YJR134C Protein of unknown function physical 1 1 1 Two-hybrid
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Two-hybrid
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Two-hybrid
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
TRE1 YPL176C Transferrin receptor-like protein genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Synthetic Lethality
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Synthetic Lethality
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Positive Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Positive Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Negative Genetic
PAU24 YBR301W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Positive Genetic