Standard name Systematic name Name description Description
LSB1 YGR136W Negative regulator of actin nucleation-promoting factor activity Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication
Visualize the interactome of LSB1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.963 0.93 0.958

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
LSB1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LAS17 YOR181W Actin assembly factor physical 8 4 5 Two-hybrid, Affinity Capture-Western, Protein-peptide, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Luminescence, Affinity Capture-Western
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 5 4 5 Affinity Capture-MS, Biochemical Activity, Reconstituted Complex, Protein-peptide, Affinity Capture-MS
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity physical 5 3 2 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Co-localization
MCA1 YOR197W Ca2+-dependent cysteine protease physical 2 2 2 Two-hybrid, Affinity Capture-MS
ACF2 YLR144C Intracellular beta-1,3-endoglucanase physical 2 2 2 Affinity Capture-MS, Two-hybrid
PEF1 YGR058W Penta-EF-hand protein physical 2 1 2 Two-hybrid, Two-hybrid
SUP35 YDR172W Translation termination factor eRF3 physical 2 1 2 Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MAC1 YMR021C Copper-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Co-localization
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
APP1 YNL094W Phosphatidate phosphatase, converts phosphatidate to diacylglycerol physical 1 1 1 Two-hybrid
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Two-hybrid
MET31 YPL038W Zinc-finger DNA-binding transcription factor physical 1 1 1 Two-hybrid
MSB3 YNL293W Rab GTPase-activating protein physical 1 1 1 Two-hybrid
UBI4 YLL039C Ubiquitin physical 1 1 1 Two-hybrid
WWM1 YFL010C WW domain containing protein of unknown function physical 1 1 1 Protein-peptide
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity genetic 1 1 1 Phenotypic Enhancement
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Positive Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase genetic 1 1 1 Negative Genetic
TOS8 YGL096W Homeodomain-containing protein and putative transcription factor genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CSM3 YMR048W Replication fork associated factor physical 1 1 1 Affinity Capture-MS
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Two-hybrid
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 Two-hybrid
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions physical 1 1 1 Two-hybrid