| NOG2 |
YNR053C |
Putative GTPase |
physical |
11 |
2 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NOG1 |
YPL093W |
Putative GTPase |
physical |
11 |
3 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
10 |
3 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
9 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
9 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
9 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
physical |
8 |
5 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
7 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
6 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
| BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
physical |
4 |
3 |
4 |
PCA, PCA, Two-hybrid, Affinity Capture-MS |
| NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
| SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NOP4 |
YPL043W |
Nucleolar protein |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
| CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
2 |
2 |
2 |
PCA, Two-hybrid |
| NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
| YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ALB1 |
YJL122W |
Shuttling pre-60S factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
| NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Two-hybrid |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
physical |
1 |
1 |
1 |
PCA |
| NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| LOC1 |
YFR001W |
Nucleolar protein involved in the asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
| NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Two-hybrid |
| MTR4 |
YJL050W |
RNA duplex-sensing translocase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Co-purification |
| RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NSA2 |
YER126C |
Protein constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Two-hybrid |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RRP17 |
YDR412W |
5' exoribonuclease required for 5' end processing of pre-60S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Two-hybrid |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TMA16 |
YOR252W |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL028C |
YBL028C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK5 |
YBR142W |
Essential nucleolar protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOC4 |
YPR144C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRK1 |
YOR267C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
physical |
1 |
1 |
1 |
Two-hybrid |
| LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Two-hybrid |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |