Standard name Systematic name Name description Description
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes Transcriptional activator of thiamine biosynthetic genes; interacts with regulatory factor Thi3p to control expression of thiamine biosynthetic genes with respect to thiamine availability; acts together with Pdc2p to respond to thiaminediphosphate demand, possibly as related to carbon source availability; zinc finger protein of the Zn(II)2Cys6 type
Visualize the interactome of THI2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
THI2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
THI74 YDR438W Mitochondrial transporter repressible by thiamine regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
THI73 YLR004C Putative plasma membrane permease regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage regulation 2 2 2 chromatin immunoprecipitation-chip evidence, northern blot evidence
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 2 1 2 Negative Genetic, Negative Genetic
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors physical 2 2 1 Two-hybrid, Reconstituted Complex
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors genetic 2 1 1 Dosage Rescue, Dosage Rescue
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SAG1 YJR004C Alpha-agglutinin of alpha-cells regulation 1 1 1 DNA to cDNA expression microarray evidence
APL1 YJR005W Beta-adaptin regulation 1 1 1 DNA to cDNA expression microarray evidence
AVO1 YOL078W Component of the membrane-bound TORC2 complex regulation 1 1 1 DNA to cDNA expression microarray evidence
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex regulation 1 1 1 DNA to cDNA expression microarray evidence
LEA1 YPL213W Component of U2 snRNP complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO3 YBR092C Constitutively expressed acid phosphatase similar to Pho5p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL150W YNL150W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
BSC3 YLR465C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
FRE1 YLR214W Ferric reductase and cupric reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
HHF1 YBR009C Histone H4 regulation 1 1 1 DNA to cDNA expression microarray evidence
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
TIM8 YJR135W-A Mitochondrial intermembrane space protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MTR10 YOR160W Nuclear import receptor regulation 1 1 1 DNA to cDNA expression microarray evidence
ORT1 YOR130C Ornithine transporter of the mitochondrial inner membrane regulation 1 1 1 DNA to cDNA expression microarray evidence
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex regulation 1 1 1 DNA to cDNA expression microarray evidence
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
THI5 YFL058W Protein involved in synthesis of the thiamine precursor HMP regulation 1 1 1 northern blot evidence
THI13 YDL244W Protein involved in synthesis of the thiamine precursor HMP regulation 1 1 1 northern blot evidence
PET18 YCR020C Protein of unknown function regulation 1 1 1 northern blot evidence
CSS1 YIL169C Protein of unknown function, secreted when constitutively expressed regulation 1 1 1 DNA to cDNA expression microarray evidence
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs regulation 1 1 1 DNA to cDNA expression microarray evidence
STE3 YKL178C Receptor for a factor pheromone regulation 1 1 1 DNA to cDNA expression microarray evidence
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPL14A YKL006W Ribosomal 60S subunit protein L14A regulation 1 1 1 DNA to cDNA expression microarray evidence
RPP1A YDL081C Ribosomal stalk protein P1 alpha regulation 1 1 1 DNA to cDNA expression microarray evidence
SBH2 YER019C-A Ssh1p-Sss1p-Sbh2p complex component regulation 1 1 1 DNA to cDNA expression microarray evidence
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
THI4 YGR144W Thiazole synthase regulation 1 1 1 northern blot evidence
PDC2 YDR081C Transcription factor for thiamine-regulated genes regulation 1 1 1 northern blot evidence
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Positive Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Co-purification
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
RNQ1 YCL028W [PIN(+)] prion genetic 1 1 1 Dosage Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Negative Genetic
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
YGR016W YGR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
CMC4 YMR194C-B Protein that localizes to the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic