Standard name Systematic name Name description Description
CAB3 YKL088W Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis; subunits of the phosphopantothenoylcysteine decarboxylase (PPCDC) complex are: Cab3p, Sis2p, Vhs3p, while the subunits of the CoA-synthesizing protein complex (CoA-SPC) are: Cab2p, Cab3p, Cab4p, and Cab5p as well as Sis2p and Vhs3p; null mutant lethality is complemented by E. coli coaBC
Visualize the interactome of CAB3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.343 0.378 NaN
Cytoplasm 0.926 0.911 NaN
ER 0.051 0.072 NaN

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CAB3 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0906 (phosphopantothenoylcysteine decarboxylase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p physical 8 5 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) physical 7 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) physical 6 4 1 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-fractionation, Two-hybrid, Two-hybrid
CAB2 YIL083C Phosphopantothenoylcysteine synthetase (PPCS) physical 5 3 1 Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS
CAB3 YKL088W Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis physical 4 4 2 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-Western
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) physical 4 3 1 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p physical 2 2 2 PCA, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Dosage Growth Defect
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
SSA3 YBL075C ATPase involved in protein folding and the response to stress physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 PCA
SUR2 YDR297W Sphinganine C4-hydroxylase physical 1 1 1 PCA
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 PCA
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 PCA
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 PCA
SCS7 YMR272C Sphingolipid alpha-hydroxylase physical 1 1 1 PCA
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
PIS1 YPR113W Phosphatidylinositol synthase physical 1 1 1 PCA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Affinity Capture-RNA
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Synthetic Lethality
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality