Standard name Systematic name Name description Description
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) Subunit II of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
Visualize the interactome of COX2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COX2 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0438 (ferrocytochrome-c:oxygen oxidoreductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
COX1 Q0045 Subunit I of cytochrome c oxidase (Complex IV) physical 9 5 9 Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Co-purification
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 7 4 6 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Co-purification
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 7 2 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RCF1 YML030W Cytochrome c oxidase subunit physical 6 4 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 6 3 4 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Synthetic Rescue, Dosage Rescue, Dosage Rescue
COX20 YDR231C Mitochondrial inner membrane protein physical 5 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification
COB Q0105 Cytochrome b physical 4 4 4 Affinity Capture-Western, Co-fractionation, Reconstituted Complex, Co-purification
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA physical 4 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
COX3 Q0275 Subunit III of cytochrome c oxidase (Complex IV) physical 4 3 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-purification
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly physical 4 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane physical 3 3 3 Affinity Capture-Western, Co-fractionation, Co-purification
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Co-purification
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Co-purification
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
TIM23 YNR017W Essential component of the TIM23 complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) physical 2 2 2 Reconstituted Complex, Co-purification
OXA1 YER154W Mitochondrial inner membrane insertase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
SHY1 YGR112W Mitochondrial inner membrane protein required for complex IV assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) physical 2 1 2 Co-purification, Co-purification
COX16 YJL003W Mitochondrial inner membrane protein physical 2 2 1 Co-purification, Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-Western
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Affinity Capture-MS
SCO2 YBR024W Protein anchored to mitochondrial inner membrane physical 1 1 1 Affinity Capture-Western
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Synthetic Rescue
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-Western
MMF1 YIL051C Mitochondrial protein required for transamination of isoleucine physical 1 1 1 Affinity Capture-MS
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Co-fractionation
MSS2 YDL107W Peripherally bound inner membrane protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-Western
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
CYT1 YOR065W Cytochrome c1 physical 1 1 1 Affinity Capture-Western
RCF2 YNR018W Cytochrome c oxidase subunit physical 1 1 1 Affinity Capture-Western
TIM21 YGR033C Nonessential component of the TIM23 complex physical 1 1 1 Affinity Capture-Western
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 Affinity Capture-Western
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RCF3 YBR255C-A Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-Western
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Affinity Capture-Western
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
COX26 YDR119W-A Subunit of cytochrome C oxidase complex physical 1 1 1 Co-purification
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis physical 1 1 1 Affinity Capture-Western
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor physical 1 1 1 Affinity Capture-Western
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
COX5A YNL052W Subunit Va of cytochrome c oxidase physical 1 1 1 Co-purification
COX9 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV) physical 1 1 1 Co-purification
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
MRP21 YBL090W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Rescue
MRP51 YPL118W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Rescue
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Synthetic Rescue
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Dosage Rescue
MRF1 YGL143C Mitochondrial translation release factor genetic 1 1 1 Synthetic Rescue
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Dosage Rescue
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Dosage Rescue
ACP1 YKL192C Mitochondrial matrix acyl carrier protein physical 1 1 1 Affinity Capture-Western
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly physical 1 1 1 Affinity Capture-Western
BXI1 YNL305C Protein involved in apoptosis physical 1 1 1 Affinity Capture-MS
COA1 YIL157C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-Western
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-Western