Standard name Systematic name Name description Description
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis
Visualize the interactome of DAD4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.057 NaN 0.168
Nucleolus 0.732 0.584 0.500
Nucleus 0.060 NaN NaN
SpindlePole 0.596 0.693 0.727
Budneck NaN 0.051 NaN
Peroxisome NaN 0.066 NaN

GFP localization & abundance

GFP localization GFP abundance
spindle pole 967

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DAD4 0 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) physical 6 4 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Co-purification, Co-purification
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 6 3 3 Co-purification, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Two-hybrid
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) physical 5 4 5 Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Reconstituted Complex
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Co-purification
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) physical 4 1 3 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 3 2 3 Affinity Capture-MS, Two-hybrid, Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 3 2 3 Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 3 3 2 PCA, Two-hybrid, FRET
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 2 2 2 Affinity Capture-MS, Two-hybrid
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Rescue
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Affinity Capture-MS
NCA2 YPR155C Protein that regulates expression of Fo-F1 ATP synthase subunits physical 1 1 1 Affinity Capture-MS
ECM13 YBL043W Non-essential protein of unknown function physical 1 1 1 Two-hybrid
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) physical 1 1 1 Two-hybrid
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Two-hybrid
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
LCP5 YER127W Essential protein involved in maturation of 18S rRNA physical 1 1 1 Two-hybrid
KEG1 YFR042W Integral membrane protein of the ER physical 1 1 1 Two-hybrid
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
REC107 YJR021C Protein involved in early stages of meiotic recombination physical 1 1 1 Two-hybrid
LDB18 YLL049W Component of the dynactin complex physical 1 1 1 Two-hybrid
MSN2 YMR037C Stress-responsive transcriptional activator physical 1 1 1 Two-hybrid
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Two-hybrid
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
PAC1 YOR269W Regulator of dynein, involved in intracellular transport physical 1 1 1 Two-hybrid
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 1 1 1 PCA
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 FRET
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA