Standard name Systematic name Name description Description
HUG1 YML058W-A Ribonucleotide reductase inhibitor Ribonucleotide reductase inhibitor; intrinsically disordered protein that binds to and inhibits Rnr2p; involved in the Mec1p-mediated checkpoint pathway; transcription is induced by genotoxic stress and by activation of the Rad53p pathway; protein abundance increases in response to DNA replication stress
Visualize the interactome of HUG1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.945 0.952 0.947
Vac/Vac Memb 0.052 NaN NaN
Mito NaN NaN 0.075

GFP localization & abundance

GFP localization GFP abundance
cytoplasm technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HUG1 0 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 3 2 2 Dosage Lethality, Synthetic Rescue, Synthetic Rescue
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
PGM2 YMR105C Phosphoglucomutase physical 2 1 2 PCA, PCA
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 2 2 1 Two-hybrid, Reconstituted Complex
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
ROX1 YPR065W Heme-dependent repressor of hypoxic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 DNA to cDNA expression microarray evidence
MOT3 YMR070W Transcriptional repressor, activator regulation 1 1 1 DNA to cDNA expression microarray evidence
ARC19 YKL013C Subunit of the ARP2/3 complex physical 1 1 1 PCA
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase physical 1 1 1 Two-hybrid
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 PCA
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 PCA
CWH41 YGL027C Processing alpha glucosidase I physical 1 1 1 PCA
ALO1 YML086C D-Arabinono-1,4-lactone oxidase physical 1 1 1 PCA
GPM2 YDL021W Nonfunctional homolog of Gpm1p phosphoglycerate mutase physical 1 1 1 PCA
INO1 YJL153C Inositol-3-phosphate synthase physical 1 1 1 PCA
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 1 1 1 PCA
SKI3 YPR189W Ski complex component and TPR protein physical 1 1 1 PCA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Reconstituted Complex
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Phenotypic Enhancement
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic