| HOP2 | YGL033W | Meiosis-specific protein that localizes to chromosomes | physical | 5 | 4 | 5 | Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Co-purification | 
            
                | LEA1 | YPL213W | Component of U2 snRNP complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | COX7 | YMR256C | Subunit VII of cytochrome c oxidase (Complex IV) | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | COX23 | YHR116W | Protein that functions in mitochondrial copper homeostasis | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | PET122 | YER153C | Mitochondrial translational activator specific for the COX3 mRNA | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | VMA21 | YGR105W | Integral membrane protein required for V-ATPase function | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | RTC6 | YPL183W-A | Protein involved in translation | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic | 
            
                | AFT2 | YPL202C | Iron-regulated transcriptional activator | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation- exonuclease evidence | 
            
                | GCR1 | YPL075W | Transcriptional activator of genes involved in glycolysis | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | REB1 | YBR049C | RNA polymerase I enhancer binding protein | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | GCN4 | YEL009C | bZIP transcriptional activator of amino acid biosynthetic genes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | AFT1 | YGL071W | Transcription factor involved in iron utilization and homeostasis | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | MEC1 | YBR136W | Genome integrity checkpoint protein and PI kinase superfamily member | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | CLB5 | YPR120C | B-type cyclin involved in DNA replication during S phase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HOP1 | YIL072W | Meiosis-specific protein required for chromosome synapsis | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | HOP2 | YGL033W | Meiosis-specific protein that localizes to chromosomes | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | HAP4 | YKL109W | Transcription factor | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GPR1 | YDL035C | Plasma membrane G protein coupled receptor (GPCR) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RRP6 | YOR001W | Nuclear exosome exonuclease component | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SPO11 | YHL022C | Meiosis-specific protein required for meiotic recombination | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | RED1 | YLR263W | Protein component of the synaptonemal complex axial elements | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | REC8 | YPR007C | Meiosis-specific component of the sister chromatid cohesion complex | genetic | 1 | 1 | 1 | Phenotypic Suppression | 
            
                | MSH4 | YFL003C | Protein involved in meiotic recombination | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SRO9 | YCL037C | Cytoplasmic RNA-binding protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SAC1 | YKL212W | Phosphatidylinositol phosphate phosphatase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UBI4 | YLL039C | Ubiquitin | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | OCA2 | YNL056W | Protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | QCR2 | YPR191W | Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPS0B | YLR048W | Protein component of the small (40S) ribosomal subunit | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | MRPL1 | YDR116C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SNF6 | YHL025W | Subunit of the SWI/SNF chromatin remodeling complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | POT1 | YIL160C | 3-ketoacyl-CoA thiolase with broad chain length specificity | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MRP49 | YKL167C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPL22A | YLR061W | Ribosomal 60S subunit protein L22A | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SIC1 | YLR079W | Cyclin-dependent kinase inhibitor (CKI) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VPS4 | YPR173C | AAA-ATPase involved in multivesicular body (MVB) protein sorting | genetic | 1 | 1 | 1 | Negative Genetic |