Standard name Systematic name Name description Description
PEX6 YNL329C AAA-peroxin AAA-peroxin; heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; mutations in human PEX6 can lead to severe peroxisomal disorders and early death
Visualize the interactome of PEX6
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.070 0.135 0.075
Endosome 0.095 NaN 0.090
Mito 0.547 0.878 0.422
Peroxisome 0.740 0.392 0.725
SpindlePole 0.161 NaN 0.221
Cort. Patches NaN 0.115 NaN

GFP localization & abundance

GFP localization GFP abundance
peroxisome 1630

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PEX6 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PEX1 YKL197C AAA-peroxin physical 30 7 14 Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Co-fractionation, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Co-fractionation, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Co-crystal Structure, Co-purification, Reconstituted Complex, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein physical 13 4 7 Two-hybrid, Reconstituted Complex, Two-hybrid, Co-fractionation, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins physical 5 3 5 Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
PEX14 YGL153W Central component of the peroxisomal importomer complex physical 4 4 4 Co-fractionation, PCA, Affinity Capture-Western, Reconstituted Complex
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 4 3 1 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid
PEX6 YNL329C AAA-peroxin physical 2 2 2 Affinity Capture-MS, PCA
PEX13 YLR191W Peroxisomal importomer complex component physical 2 2 2 Co-fractionation, Affinity Capture-Western
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex physical 2 2 2 Co-fractionation, Affinity Capture-Western
CHS7 YHR142W Protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Positive Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis physical 1 1 1 Two-hybrid
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
MRP13 YGR084C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Dosage Rescue
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
USA1 YML029W Scaffold subunit of the Hrd1p ubiquitin ligase physical 1 1 1 Affinity Capture-MS
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery physical 1 1 1 Co-fractionation
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Positive Genetic
YHL042W YHL042W Endoplasmic reticulum protein physical 1 1 1 PCA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
UBI4 YLL039C Ubiquitin physical 1 1 1 Reconstituted Complex
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Synthetic Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
YDR514C YDR514C Protein of unknown function that localizes to mitochondria genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
CHS1 YNL192W Chitin synthase I genetic 1 1 1 Synthetic Lethality
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
PEX18 YHR160C Peroxin physical 1 1 1 Affinity Capture-Western
ATG36 YJL185C Pex3p interacting protein, required for pexophagy genetic 1 1 1 Phenotypic Suppression
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase physical 1 1 1 Co-fractionation
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase physical 1 1 1 Affinity Capture-Western
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Lethality
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Positive Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
CTS1 YLR286C Endochitinase genetic 1 1 1 Synthetic Growth Defect
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Positive Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Lethality
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ITR2 YOL103W Myo-inositol transporter genetic 1 1 1 Negative Genetic
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic
MNL2 YLR057W Putative mannosidase involved in ER-associated protein degradation genetic 1 1 1 Synthetic Growth Defect