TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
47 |
5 |
41 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
physical |
15 |
3 |
9 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
TIM44 |
YIL022W |
Essential component of the TIM23 complex |
physical |
9 |
3 |
8 |
Affinity Capture-Western, Co-fractionation, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
physical |
9 |
2 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
physical |
9 |
1 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
physical |
8 |
2 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
7 |
4 |
6 |
Dosage Rescue, Synthetic Lethality, Dosage Rescue, Dosage Rescue, Phenotypic Suppression, Dosage Rescue, Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
6 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
1 |
4 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
physical |
4 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
TIM44 |
YIL022W |
Essential component of the TIM23 complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MIA40 |
YKL195W |
Import and assembly protein in mitochondrial intermembrane space |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM17 |
YJL143W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CYB2 |
YML054C |
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
MRPL40 |
YPL173W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ERV1 |
YGR029W |
Flavin-linked sulfhydryl oxidase of the mitochondrial IMS |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MIX23 |
YBL107C |
Mitochondrial intermembrane space protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |