Standard name Systematic name Name description Description
SLD7 YOR060C Protein with a role in chromosomal DNA replication Protein with a role in chromosomal DNA replication; interacts with Sld3p and reduces its affinity for Cdc45p; deletion mutant has aberrant mitochondria; ortholog of human MTBP, which is a DNA replication origin firing factor
Visualize the interactome of SLD7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.111 0.118 0.368
Mito 0.500 0.804 NaN
Nucleus 0.611 0.216 0.414
Vac/Vac Memb 0.056 0.176 0.172
SpindlePole NaN NaN 0.080

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SLD7 0 0 0 0 2

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SLD3 YGL113W Protein involved in the initiation of DNA replication physical 7 4 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-fractionation, Two-hybrid, Reconstituted Complex, Two-hybrid
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 4 3 2 Dosage Rescue, Dosage Rescue, Dosage Growth Defect, Phenotypic Enhancement
DPB11 YJL090C DNA replication initiation protein genetic 3 3 2 Dosage Rescue, Dosage Growth Defect, Phenotypic Enhancement
CDC45 YLR103C DNA replication initiation factor genetic 2 2 2 Dosage Rescue, Dosage Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein genetic 2 2 1 Dosage Growth Defect, Phenotypic Enhancement
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 2 1 Dosage Growth Defect, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Suppression
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein physical 1 1 1 Reconstituted Complex
DPB11 YJL090C DNA replication initiation protein physical 1 1 1 Two-hybrid
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Lethality
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Lethality
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Phenotypic Suppression
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Dosage Rescue