Standard name Systematic name Name description Description
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions Cytochrome c isoform 2, expressed under hypoxic conditions; also known as iso-2-cytochrome c; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; protein abundance increases in response to DNA replication stress; CYC7 has a paralog, CYC1, that arose from the whole genome duplication
Visualize the interactome of CYC7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.977 0.982 0.957

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1310

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CYC7 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0002 ((R)-lactate:ferricytochrome-c 2-oxidoreductase), r_0004 ((S)-lactate:ferricytochrome-c 2-oxidoreductase), r_0437 (ferrocytochrome-c:hydrogen-peroxide oxidoreductase), r_0439 (ubiquinol:ferricytochrome c reductase), r_0001 ((R)-lactate:ferricytochrome-c 2-oxidoreductase), r_0438 (ferrocytochrome-c:oxygen oxidoreductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CYC1 YJR048W Cytochrome c, isoform 1 genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 beta-galactosidase reporter gene assay evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HIR3 YJR140C Subunit of the HIR complex regulation 1 1 1 DNA to cDNA expression microarray evidence
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
COX14 YML129C Mitochondrial cytochrome c oxidase (complex IV) assembly factor genetic 1 1 1 Phenotypic Suppression
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Dosage Rescue
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone physical 1 1 1 Affinity Capture-MS
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator physical 1 1 1 PCA
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 PCA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NVJ1 YHR195W Nuclear envelope protein physical 1 1 1 PCA
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space physical 1 1 1 Biochemical Activity
ERV1 YGR029W Flavin-linked sulfhydryl oxidase of the mitochondrial IMS physical 1 1 1 Biochemical Activity
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Reconstituted Complex
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Synthetic Lethality
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS