Standard name Systematic name Name description Description
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor MAP kinase-responsive inhibitor of the Ste12p transcription factor; involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p; DIG2 has a paralog, DIG1, that arose from the whole genome duplication
Visualize the interactome of DIG2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 46

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.770 0.760 0.759
Mito 0.068 0.055 0.076
Nucleus 0.088 NaN NaN
Vac/Vac Memb 0.149 0.130 0.139
Endosome NaN 0.058 0.094

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1310

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DIG2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 12 5 9 Reconstituted Complex, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 11 4 8 Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 8 4 7 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity, Two-hybrid, Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 5 3 4 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 3 2 3 Two-hybrid, Affinity Capture-Western, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SRP1 YNL189W Karyopherin alpha homolog physical 2 2 2 Affinity Capture-MS, Two-hybrid
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CNA1 YLR433C Calcineurin A physical 2 2 1 Reconstituted Complex, Biochemical Activity
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BUD14 YAR014C Protein involved in bud-site selection physical 1 1 1 Two-hybrid
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 1 1 1 Two-hybrid
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Two-hybrid
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
CMP2 YML057W Calcineurin A physical 1 1 1 Reconstituted Complex
MSC7 YHR039C Protein of unknown function physical 1 1 1 Two-hybrid
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Synthetic Rescue
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
HMLALPHA1 YCL066W Silenced copy of ALPHA1 at HML physical 1 1 1 Two-hybrid
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex physical 1 1 1 Two-hybrid
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Two-hybrid
MRX12 YJR003C Protein that associates with mitochondrial ribosome physical 1 1 1 Two-hybrid
HYM1 YKL189W Component of the RAM signaling network physical 1 1 1 Two-hybrid
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
PEX13 YLR191W Peroxisomal importomer complex component physical 1 1 1 Two-hybrid
KDX1 YKL161C Protein kinase physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Rescue
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Synthetic Lethality
RNH202 YDR279W Ribonuclease H2 subunit genetic 1 1 1 Positive Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Positive Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Phenotypic Suppression
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Phenotypic Enhancement
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Positive Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Positive Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Positive Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Positive Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic
YPR114W YPR114W Protein distantly similar to ceramide synthases, Lag1p and Lac1p genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle physical 1 1 1 Two-hybrid
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle physical 1 1 1 Two-hybrid
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 1 1 1 Two-hybrid
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic