Standard name Systematic name Name description Description
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase S-adenosylmethionine-dependent lysine methyltransferase; involved in the trimethylation of eEF1A (Tef1p/Tef2p) at lysine 79; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in budding yeast; expresses a circular RNA; originally misclassified as a N-6-adenine specific DNA methyltransferase based on sequence similarity; both Efm5p and human ortholog N6AMT2 can methylate eEF1a from either species in vitro
Visualize the interactome of EFM5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.995 0.997 0.991

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
EFM5 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ATG5 YPL149W Conserved protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Reconstituted Complex
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Positive Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Biochemical Activity
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
KIN1 YDR122W S/T protein kinase physical 1 1 1 Reconstituted Complex
KIN2 YLR096W S/T protein kinase physical 1 1 1 Reconstituted Complex
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Reconstituted Complex
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 1 1 1 PCA
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ZIP2 YGL249W Meiosis-specific protein physical 1 1 1 Affinity Capture-MS
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Positive Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Negative Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YEF1 YEL041W ATP-NADH kinase genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
SRX1 YKL086W Sulfiredoxin genetic 1 1 1 Negative Genetic
YEH2 YLR020C Steryl ester hydrolase genetic 1 1 1 Negative Genetic
SSP120 YLR250W Protein packaged into COPII vesicles for ER to Golgi trafficking genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
WTM1 YOR230W Transcriptional modulator genetic 1 1 1 Negative Genetic
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
AIM24 YJR080C Protein with a role in determining mitochondrial architecture genetic 1 1 1 Negative Genetic