| UGA1 |
YGR019W |
Gamma-aminobutyrate (GABA) transaminase |
genetic |
5 |
3 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement |
| UGA2 |
YBR006W |
Succinate semialdehyde dehydrogenase |
genetic |
3 |
3 |
1 |
Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement |
| HCM1 |
YCR065W |
Forkhead transcription factor |
regulation |
2 |
2 |
2 |
quantitative polymerase chain reaction evidence, quantitative reverse transcription polymerase chain reaction evidence |
| GAD1 |
YMR250W |
Glutamate decarboxylase |
physical |
2 |
1 |
2 |
PCA, PCA |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RGM1 |
YMR182C |
Putative zinc finger DNA binding transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| WTM2 |
YOR229W |
Transcriptional modulator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CUP2 |
YGL166W |
Copper-binding transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FLO8 |
YER109C |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ADE13 |
YLR359W |
Adenylosuccinate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
PCA |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADE8 |
YDR408C |
Phosphoribosyl-glycinamide transformylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRS2 |
YPR081C |
Glycine-tRNA synthetase, not expressed under normal growth conditions |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MUP3 |
YHL036W |
Low affinity methionine permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR034C-A |
YOR034C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC59 |
YMR013C |
Dolichol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AVT6 |
YER119C |
Vacuolar aspartate and glutamate exporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUZ1 |
YNL155W |
Protein with a role in the ubiquitin-proteasome pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM23 |
YJL131C |
Mitochondrial translation initiation factor 3 (IF3, mIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR4 |
YCR069W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX16 |
YJL003W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |