| Standard name | Systematic name | Name description | Description |
|---|---|---|---|
| LEU2 | YCL018W | Beta-isopropylmalate dehydrogenase (IMDH) | Beta-isopropylmalate dehydrogenase (IMDH); catalyzes the third step in the leucine biosynthesis pathway; can additionally catalyze the conversion of beta-ethylmalate into alpha-ketovalerate |
Cell cycle phase and timing of transcription peak
| Cell cycle phase | Time (min) |
|---|---|
CYCLoPs localization & abundance
| WT1 | WT2 | WT3 |
|---|---|---|
| no data | no data | no data |
GFP localization & abundance
| GFP localization | GFP abundance |
|---|---|
| no data | no data |
GO term count
| Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
|---|---|---|---|---|---|
| LEU2 | 2 | 0 | 0 | 0 | 0 |
Enzyme information
| Catalyzed reactions in Yeast8 |
|---|
| r_0061 (3-isopropylmalate dehydrogenase) |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.| Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
|---|---|---|---|---|---|---|---|
| SSY1 | YDR160W | Component of the SPS plasma membrane amino acid sensor system | genetic | 2 | 1 | 2 | Synthetic Lethality, Synthetic Lethality |
| SFP1 | YLR403W | Regulates transcription of ribosomal protein and biogenesis genes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| TYE7 | YOR344C | Serine-rich protein that contains a bHLH DNA binding motif | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| LEU3 | YLR451W | Zinc-knuckle transcription factor, repressor and activator | regulation | 1 | 1 | 1 | beta-galactosidase reporter gene assay evidence |
| CDC73 | YLR418C | Component of the Paf1p complex | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| PUT3 | YKL015W | Transcriptional activator | regulation | 1 | 1 | 1 | northern blot evidence |
| HMS1 | YOR032C | bHLH protein with similarity to myc-family transcription factors | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| YAP3 | YHL009C | Basic leucine zipper (bZIP) transcription factor | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| ESA1 | YOR244W | Catalytic subunit of the histone acetyltransferase complex (NuA4) | genetic | 1 | 1 | 1 | Dosage Rescue |
| ERO1 | YML130C | Thiol oxidase required for oxidative protein folding in the ER | genetic | 1 | 1 | 1 | Synthetic Growth Defect |
| GCN2 | YDR283C | Protein kinase | genetic | 1 | 1 | 1 | Dosage Rescue |
| ESP1 | YGR098C | Separase/separin, a caspase-like cysteine protease | physical | 1 | 1 | 1 | Affinity Capture-MS |
| HSC82 | YMR186W | Cytoplasmic chaperone of the Hsp90 family | physical | 1 | 1 | 1 | Affinity Capture-MS |
| HSP82 | YPL240C | Hsp90 chaperone | physical | 1 | 1 | 1 | Affinity Capture-MS |
| GAP1 | YKR039W | General amino acid permease | genetic | 1 | 1 | 1 | Dosage Rescue |
| HAC1 | YFL031W | Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| LEU1 | YGL009C | Isopropylmalate isomerase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| ATF1 | YOR377W | Alcohol acetyltransferase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| HRQ1 | YDR291W | 3'-5' DNA helicase of the conserved RecQ family | physical | 1 | 1 | 1 | Affinity Capture-MS |
| PHO85 | YPL031C | Cyclin-dependent kinase | physical | 1 | 1 | 1 | Biochemical Activity |
| SMC3 | YJL074C | Subunit of the multiprotein cohesin complex | physical | 1 | 1 | 1 | Affinity Capture-MS |
| SMC4 | YLR086W | Subunit of the condensin complex | physical | 1 | 1 | 1 | Affinity Capture-MS |
| SPB4 | YFL002C | Putative ATP-dependent RNA helicase | physical | 1 | 1 | 1 | Affinity Capture-MS |
| NAM7 | YMR080C | ATP-dependent RNA helicase of the SFI superfamily | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| RPC82 | YPR190C | RNA polymerase III subunit C82 | physical | 1 | 1 | 1 | Affinity Capture-MS |
| VTS1 | YOR359W | Flap-structured DNA-binding and RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| PTR3 | YFR029W | Component of the SPS plasma membrane amino acid sensor system | genetic | 1 | 1 | 1 | Synthetic Lethality |
| YFH1 | YDL120W | Mitochondrial matrix iron chaperone | genetic | 1 | 1 | 1 | Dosage Rescue |
| SUI2 | YJR007W | Alpha subunit of the translation initiation factor eIF2 | genetic | 1 | 1 | 1 | Synthetic Growth Defect |