Standard name Systematic name Name description Description
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase Delta 1-pyrroline-5-carboxylate reductase; catalyzes the last step in proline biosynthesis
Visualize the interactome of PRO3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.995 0.982 0.977

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 43500

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRO3 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0687 (L-hydroxyproline reductase (NADP)), r_0957 (pyrroline-5-carboxylate reductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 3 2 3 Affinity Capture-MS, PCA, PCA
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 3 2 3 Two-hybrid, PCA, Two-hybrid
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 2 2 2 Affinity Capture-MS, Two-hybrid
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 2 2 1 Two-hybrid, PCA
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Biochemical Activity
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Synthetic Lethality
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Lethality
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 1 1 1 Reconstituted Complex
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SAN1 YDR143C Ubiquitin-protein ligase physical 1 1 1 Two-hybrid
SAN1 YDR143C Ubiquitin-protein ligase genetic 1 1 1 Synthetic Rescue
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YKR104W YKR104W Putative transporter of the MRP subfamily physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Synthetic Growth Defect
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Phenotypic Suppression
PUT4 YOR348C Proline permease genetic 1 1 1 Synthetic Lethality
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Synthetic Rescue
PUT1 YLR142W Proline oxidase genetic 1 1 1 Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 1 1 1 Two-hybrid
GAP1 YKR039W General amino acid permease genetic 1 1 1 Synthetic Lethality
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
ATX1 YNL259C Cytosolic copper metallochaperone physical 1 1 1 PCA
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
NFT1 YKR103W Putative transporter of the MRP subfamily physical 1 1 1 PCA