| PTR3 |
YFR029W |
Component of the SPS plasma membrane amino acid sensor system |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-Western, Two-hybrid |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| SSY5 |
YJL156C |
Serine protease of SPS plasma membrane amino acid sensor system |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Two-hybrid |
| DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| SSY5 |
YJL156C |
Serine protease of SPS plasma membrane amino acid sensor system |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PFU1 |
YDR306C |
F-box protein that regulates pheromone-dependent morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASI3 |
YNL008C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PEX18 |
YHR160C |
Peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYH1 |
YPL105C |
Protein of unknown function that influences nuclear pore distribution |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HYR1 |
YIR037W |
Glutathione peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYR1 |
YIR037W |
Glutathione peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASI1 |
YMR119W |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| LEU2 |
YCL018W |
Beta-isopropylmalate dehydrogenase (IMDH) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |