| SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
9 |
4 |
8 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
4 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
4 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
| UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BDH1 |
YAL060W |
NAD-dependent (R,R)-butanediol dehydrogenase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| THI2 |
YBR240C |
Transcriptional activator of thiamine biosynthetic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PIP2 |
YOR363C |
Autoregulatory, oleate-activated transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
PCA |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SPC2 |
YML055W |
Subunit of signal peptidase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
physical |
1 |
1 |
1 |
PCA |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
physical |
1 |
1 |
1 |
PCA |
| SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
PCA |
| SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
physical |
1 |
1 |
1 |
PCA |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
physical |
1 |
1 |
1 |
PCA |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
physical |
1 |
1 |
1 |
PCA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |