Standard name Systematic name Name description Description
SPL2 YHR136C Protein with similarity to cyclin-dependent kinase inhibitors Protein with similarity to cyclin-dependent kinase inhibitors; downregulates low-affinity phosphate transport during phosphate limitation by targeting Pho87p to the vacuole; upstream region harbors putative hypoxia response element (HRE) cluster; overproduction suppresses a plc1 null mutation; promoter shows an increase in Snf2p occupancy after heat shock; GFP-fusion protein localizes to the cytoplasm
Visualize the interactome of SPL2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2/M 133

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.884 0.956 0.948
Vac/Vac Memb 0.060 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
punctate composite 2180

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SPL2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 4 3 3 Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
PLC1 YPL268W Phospholipase C genetic 2 2 1 Dosage Rescue, Phenotypic Enhancement
PHO90 YJL198W Low-affinity phosphate transporter physical 2 2 1 PCA, Affinity Capture-Western
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN1 YOL116W Transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 northern blot evidence
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
WTM2 YOR229W Transcriptional modulator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MOT3 YMR070W Transcriptional repressor, activator regulation 1 1 1 DNA to cDNA expression microarray evidence
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors regulation 1 1 1 DNA to cDNA expression microarray evidence
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex regulation 1 1 1 northern blot evidence
INO80 YGL150C Nucleosome spacing factor regulation 1 1 1 northern blot evidence
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling regulation 1 1 1 northern blot evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism genetic 1 1 1 Phenotypic Suppression
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 1 1 1 Positive Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Dosage Rescue
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
ERV15 YBR210W Protein involved in export of proteins from the endoplasmic reticulum genetic 1 1 1 Negative Genetic
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PHO90 YJL198W Low-affinity phosphate transporter genetic 1 1 1 Phenotypic Suppression
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 PCA
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Negative Genetic
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter physical 1 1 1 PCA
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 1 1 1 Positive Genetic
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
TRM82 YDR165W Noncatalytic subunit of a tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
YDR222W YDR222W Protein of unknown function genetic 1 1 1 Negative Genetic
YGL081W YGL081W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Negative Genetic