Standard name Systematic name Name description Description
TRR2 YHR106W Mitochondrial thioredoxin reductase Mitochondrial thioredoxin reductase; involved in protection against oxidative stress, required with Glr1p to maintain the redox state of Trx3p; contains active-site motif (CAVC) present in prokaryotic orthologs; binds NADPH and FAD; TRR2 has a paralog, TRR1, that arose from the whole genome duplication
Visualize the interactome of TRR2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.226 0.348 0.674
Mito 0.798 0.486 0.073
Cell Periphery NaN 0.065 NaN
Cort. Patches NaN 0.058 NaN
ER NaN 0.072 NaN
Endosome NaN 0.094 NaN
Budneck NaN NaN 0.064
SpindlePole NaN NaN 0.124

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 414

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TRR2 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1039 (thioredoxin reductase (NADPH))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase genetic 7 3 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect
TRR1 YDR353W Cytoplasmic thioredoxin reductase physical 4 3 4 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS
TRR1 YDR353W Cytoplasmic thioredoxin reductase genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
TRX3 YCR083W Mitochondrial thioredoxin genetic 3 3 2 Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 2 2 2 Negative Genetic, Synthetic Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Positive Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex physical 1 1 1 Two-hybrid
ILV3 YJR016C Dihydroxyacid dehydratase genetic 1 1 1 Positive Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Rescue
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Positive Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ATG8 YBL078C Ub-like protein genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
LEU1 YGL009C Isopropylmalate isomerase genetic 1 1 1 Positive Genetic
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Positive Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 1 1 1 Negative Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 1 1 1 Phenotypic Suppression
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
TRX3 YCR083W Mitochondrial thioredoxin physical 1 1 1 Biochemical Activity
TRR2 YHR106W Mitochondrial thioredoxin reductase physical 1 1 1 Affinity Capture-MS
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Positive Genetic