Standard name Systematic name Name description Description
YPR1 YDR368W NADPH-dependent aldo-keto reductase NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant
Visualize the interactome of YPR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 154

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.992 0.995 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 14100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YPR1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_4672 (aldehyde dehydrogenase (tyrosol, NADP)), r_4654 (aldehyde dehydrogenase (1-propanol, NADP)), r_0164 (alcohol dehydrogenase (glycerol, NADP)), r_0168 (aldehyde dehydrogenase (2-methylbutanol, NADP)), r_4663 (aldehyde dehydrogenase (methionol, NADP))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GRE3 YHR104W Aldose reductase genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 2 1 2 Negative Genetic, Negative Genetic
LUG1 YLR352W Protein of unknown function with similarity to F-box proteins genetic 2 1 2 Negative Genetic, Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 2 1 2 Negative Genetic, Negative Genetic
REH1 YLR387C Cytoplasmic 60S subunit biogenesis factor genetic 2 1 2 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CHA4 YLR098C DNA binding transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ECM29 YHL030W Scaffold protein genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 PCA
MAM33 YIL070C Acidic protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Growth Defect
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Positive Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
APE2 YKL157W Aminopeptidase yscII genetic 1 1 1 Negative Genetic
GCY1 YOR120W Glycerol dehydrogenase genetic 1 1 1 Synthetic Growth Defect
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Affinity Capture-MS
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Negative Genetic
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic