Standard name Systematic name Name description Description
ALK1 YGL021W Atypical protein kinase Atypical protein kinase; along with paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of formins and polarisome components in mitosis, and survival after spindle assembly checkpoint delay; regulates the morphogenesis checkpoint in response to polarity insults through inactivation of Mih1p; phosphorylated in response to DNA damage; similar to mammalian haspins
Visualize the interactome of ALK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2 130

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.051 NaN 0.076
Cytoplasm 0.974 0.957 0.956

GFP localization & abundance

GFP localization GFP abundance
ambiguous 2190

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ALK1 1 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH2 YNL068C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKH1 YIL131C Forkhead family transcription factor regulation 3 3 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
DAK1 YML070W Dihydroxyacetone kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ALK2 YBL009W Atypical protein kinase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Suppression
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NDD1 YOR372C Transcriptional activator essential for nuclear division regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MCM1 YMR043W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family physical 1 1 1 PCA
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family physical 1 1 1 PCA
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Lethality
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
YAR028W YAR028W Putative integral membrane protein genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
ERJ5 YFR041C Type I membrane protein with a J domain genetic 1 1 1 Negative Genetic
SAP4 YGL229C Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
YGL230C YGL230C Putative protein of unknown function genetic 1 1 1 Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
YLR456W YLR456W Protein of unknown function genetic 1 1 1 Negative Genetic
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
CWP2 YKL096W-A Covalently linked cell wall mannoprotein genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Phenotypic Suppression
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Phenotypic Suppression
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Suppression