Standard name Systematic name Name description Description
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication
Visualize the interactome of AUS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
AUS1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1147 (ergosterol transport), r_2107 (zymosterol transport), r_1162 (fecosterol transport), r_1225 (lanosterol transport), r_1278 (zymosterol transport), r_1148 (ergosterol transport), r_1146 (episterol transport), r_1161 (fecosterol transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PCA1 YBR295W Cadmium transporting P-type ATPase genetic 2 1 2 Positive Genetic, Positive Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 2 1 2 Negative Genetic, Negative Genetic
YDR476C YDR476C Putative protein of unknown function physical 2 1 1 PCA, PCA
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p physical 2 1 1 PCA, PCA
NSG2 YNL156C Protein involved in regulation of sterol biosynthesis physical 2 1 1 PCA, PCA
HXT5 YHR096C Hexose transporter with moderate affinity for glucose physical 2 1 1 PCA, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MOT3 YMR070W Transcriptional repressor, activator regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Affinity Capture-Western
MSL1 YIR009W U2B component of U2 snRNP physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YJR096W YJR096W Xylose and arabinose reductase physical 1 1 1 Protein-peptide
NPT1 YOR209C Nicotinate phosphoribosyltransferase physical 1 1 1 Protein-peptide
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Protein-peptide
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle physical 1 1 1 Protein-peptide
THI80 YOR143C Thiamine pyrophosphokinase physical 1 1 1 Protein-peptide
YMR196W YMR196W Putative protein of unknown function physical 1 1 1 Protein-peptide
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Protein-peptide
YIL060W YIL060W Mitochondrial protein of unknown function physical 1 1 1 Protein-peptide
PAN5 YHR063C 2-dehydropantoate 2-reductase physical 1 1 1 Protein-peptide
NPL3 YDR432W RNA-binding protein physical 1 1 1 Protein-peptide
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space physical 1 1 1 Protein-peptide
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Protein-peptide
PRO2 YOR323C Gamma-glutamyl phosphate reductase physical 1 1 1 Protein-peptide
TUM1 YOR251C Rhodanese domain sulfur transferase physical 1 1 1 Protein-peptide
GPM3 YOL056W Nonfunctional homolog of Gpm1p phosphoglycerate mutase physical 1 1 1 Protein-peptide
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Protein-peptide
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 1 1 1 Protein-peptide
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 physical 1 1 1 PCA
MTC4 YBR255W Protein of unknown function physical 1 1 1 PCA
ERP3 YDL018C Protein with similarity to Emp24p and Erv25p physical 1 1 1 PCA
VBA4 YDR119W Protein of unknown function physical 1 1 1 PCA
ITR1 YDR497C Myo-inositol transporter physical 1 1 1 PCA
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 PCA
YHL008C YHL008C Putative protein of unknown function physical 1 1 1 PCA
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 PCA
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 PCA
YJR015W YJR015W Putative protein of unknown function physical 1 1 1 PCA
HXT16 YJR158W Putative transmembrane polyol transporter physical 1 1 1 PCA
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 PCA
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine physical 1 1 1 PCA
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 PCA
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex physical 1 1 1 PCA
SPT14 YPL175W UDP-glycosyltransferase subunit of the GPI-GnT complex physical 1 1 1 PCA
GUP2 YPL189W Probable membrane protein physical 1 1 1 PCA
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen physical 1 1 1 PCA
FUR4 YBR021W Plasma membrane localized uracil permease physical 1 1 1 PCA
PDR11 YIL013C ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Synthetic Growth Defect
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
CAR2 YLR438W L-ornithine transaminase (OTAse) genetic 1 1 1 Positive Genetic
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex genetic 1 1 1 Positive Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Positive Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Positive Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
YLR162W YLR162W Protein of unknown function genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
ADE12 YNL220W Adenylosuccinate synthase physical 1 1 1 Protein-peptide