Standard name Systematic name Name description Description
CRS1 YNL247W Cysteinyl-tRNA synthetase Cysteinyl-tRNA synthetase; CRS1 has two in-frame start codons resulting in a shorter isoform that is retained in the cytosol and a longer form that is mitochondrial; may interact with ribosomes, based on co-purification experiments; human gene CARS allows growth of the yeast haploid null mutant after sporulation of a heterozygous diploid
Visualize the interactome of CRS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CRS1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0313 (cysteinyl-tRNA synthetase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CRS1 YNL247W Cysteinyl-tRNA synthetase physical 2 2 2 Co-purification, PCA
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 PCA
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
SRM1 YGL097W Nucleotide exchange factor for Gsp1p physical 1 1 1 Affinity Capture-MS
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Affinity Capture-MS
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Affinity Capture-MS
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Synthetic Lethality
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Positive Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
TIM44 YIL022W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Negative Genetic
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
HEL2 YDR266C RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ECM19 YLR390W Protein of unknown function genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Positive Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Positive Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic