Standard name Systematic name Name description Description
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain
Visualize the interactome of MUK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.884 0.912 0.829
ER NaN 0.065 0.146

GFP localization & abundance

GFP localization GFP abundance
cytoplasm no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MUK1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 10 3 8 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 4 1 4 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
ADY3 YDL239C Protein required for spore wall formation physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, PCA
VPS5 YOR069W Nexin-1 homolog physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, PCA
VPS21 YOR089C Endosomal Rab family GTPase physical 3 2 2 Two-hybrid, Two-hybrid, PCA
CDD1 YLR245C Cytidine deaminase physical 2 1 2 Two-hybrid, Two-hybrid
HPA2 YPR193C Tetrameric histone acetyltransferase physical 2 1 2 Two-hybrid, Two-hybrid
YPT6 YLR262C Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
YPK1 YKL126W S/T protein kinase physical 2 1 2 Biochemical Activity, Biochemical Activity
ILM1 YJR118C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YPK1 YKL126W S/T protein kinase regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
PEP8 YJL053W Vacuolar protein component of the retromer physical 2 2 1 Affinity Capture-Western, PCA
YML002W YML002W Putative protein of unknown function genetic 2 2 1 Dosage Rescue, Dosage Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 1 1 1 Two-hybrid
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Two-hybrid
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
ISN1 YOR155C Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase physical 1 1 1 Two-hybrid
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
ARP1 YHR129C Actin-related protein of the dynactin complex physical 1 1 1 Two-hybrid
ECM31 YBR176W Ketopantoate hydroxymethyltransferase physical 1 1 1 Two-hybrid
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase physical 1 1 1 Two-hybrid
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
AMD1 YML035C AMP deaminase physical 1 1 1 Two-hybrid
EMC5 YIL027C Member of conserved ER transmembrane complex physical 1 1 1 PCA
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) physical 1 1 1 Two-hybrid
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
DYS1 YHR068W Deoxyhypusine synthase physical 1 1 1 Two-hybrid
CAT2 YML042W Carnitine acetyl-CoA transferase physical 1 1 1 Two-hybrid
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity physical 1 1 1 Two-hybrid
SMC5 YOL034W Subunit of the SMC5-SMC6 complex physical 1 1 1 Two-hybrid
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) physical 1 1 1 Two-hybrid
NNR2 YKL151C Widely-conserved NADHX dehydratase physical 1 1 1 Two-hybrid
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid physical 1 1 1 Two-hybrid
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Two-hybrid
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 1 1 1 Two-hybrid
YJL218W YJL218W Mitochondrial protein, putative acetyltransferase physical 1 1 1 Two-hybrid
YIP3 YNL044W Protein localized to COPII vesicles physical 1 1 1 Two-hybrid
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Two-hybrid
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator physical 1 1 1 Two-hybrid
YPL088W YPL088W Putative aryl alcohol dehydrogenase physical 1 1 1 Two-hybrid
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Two-hybrid
SNO1 YMR095C Protein of unconfirmed function physical 1 1 1 Two-hybrid
SNZ3 YFL059W Pyridoxal-5'-phosphate synthase physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
YPT7 YML001W Rab family GTPase physical 1 1 1 Two-hybrid
YIP1 YGR172C Integral membrane protein physical 1 1 1 Two-hybrid
YPT6 YLR262C Rab family GTPase physical 1 1 1 Two-hybrid
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Dosage Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
VPS17 YOR132W Subunit of the membrane-associated retromer complex physical 1 1 1 Affinity Capture-Western
VPS29 YHR012W Subunit of the membrane-associated retromer complex physical 1 1 1 Affinity Capture-Western
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
NBP1 YLR457C Spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
YML003W YML003W Putative protein of unknown function genetic 1 1 1 Dosage Rescue
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Positive Genetic
CTA1 YDR256C Catalase A physical 1 1 1 Two-hybrid
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic