VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
2 |
2 |
2 |
Two-hybrid, Co-fractionation |
STE13 |
YOR219C |
Dipeptidyl aminopeptidase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
PCA |
RBD2 |
YPL246C |
Possible rhomboid protease |
physical |
1 |
1 |
1 |
Two-hybrid |
AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
JHD2 |
YJR119C |
JmjC domain family histone demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
physical |
1 |
1 |
1 |
PCA |
FTR1 |
YER145C |
High affinity iron permease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIF1 |
YNL263C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
YIP1 |
YGR172C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT53 |
YNL093W |
Stress-induced Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
YLR031W |
YLR031W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SPP382 |
YLR424W |
Essential protein that forms a dimer with Ntr2p |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SNX41 |
YDR425W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML020W |
YML020W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |