SRL2 |
YLR082C |
Protein of unknown function |
physical |
4 |
1 |
4 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRI1 |
YDL216C |
Catalytic subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
physical |
1 |
1 |
1 |
Two-hybrid |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ETP1 |
YHL010C |
Protein of unknown function required for growth on ethanol |
physical |
1 |
1 |
1 |
Two-hybrid |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
PCA |
YHL009W-B |
YHL009W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL216W |
YPL216W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLL053C |
YLL053C |
Putative protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YEF1 |
YEL041W |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER134C |
YER134C |
Magnesium-dependent acid phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR240C-A |
YGR240C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR321C |
YMR321C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL194C |
YNL194C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL159C-A |
YOL159C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Two-hybrid |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP5 |
YNL059C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Two-hybrid |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPA2 |
YLL021W |
Component of the polarisome |
physical |
1 |
1 |
1 |
Two-hybrid |
HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
REV1 |
YOR346W |
Deoxycytidyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
physical |
1 |
1 |
1 |
Two-hybrid |
CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
PCA |
MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
physical |
1 |
1 |
1 |
Two-hybrid |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUP1-2 |
YHR055C |
Metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Two-hybrid |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Positive Genetic |