Standard name Systematic name Name description Description
TGL1 YKL140W Steryl ester hydrolase Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
Visualize the interactome of TGL1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.328 0.422 0.511
Endosome 0.190 0.357 0.058
Mito 0.129 0.106 0.172
Nucleus 0.052 NaN NaN
Peroxisome 0.121 0.166 NaN
SpindlePole 0.362 0.234 0.288

GFP localization & abundance

GFP localization GFP abundance
punctate composite 1470

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TGL1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_3253 (ergosteryl ester hydrolase (18:1), lipid particle), r_3252 (ergosteryl ester hydrolase (16:1), lipid particle)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter physical 2 2 2 Co-fractionation, PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
YEH1 YLL012W Steryl ester hydrolase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
YEH2 YLR020C Steryl ester hydrolase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
PIL1 YGR086C Eisosome core component genetic 2 1 1 Negative Genetic, Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 2 1 1 Positive Genetic, Positive Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP genetic 2 1 1 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 2 1 1 Positive Genetic, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-MS
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Positive Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase physical 1 1 1 PCA
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Biochemical Activity
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Affinity Capture-MS
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
SNA3 YJL151C Protein involved in efficient MVB sorting of proteins to the vacuole physical 1 1 1 PCA
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Positive Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ACF2 YLR144C Intracellular beta-1,3-endoglucanase physical 1 1 1 PCA
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation physical 1 1 1 Affinity Capture-MS
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
ERG7 YHR072W Lanosterol synthase physical 1 1 1 PCA
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase physical 1 1 1 PCA
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Positive Genetic
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 physical 1 1 1 PCA
TGL1 YKL140W Steryl ester hydrolase physical 1 1 1 PCA
YIM1 YMR152W Aldehyde reductase physical 1 1 1 PCA
YPT7 YML001W Rab family GTPase physical 1 1 1 Affinity Capture-MS
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Positive Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic