Standard name Systematic name Name description Description
BUD32 YGR262C Protein kinase Protein kinase; component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; Pyrococcus Bud32 ortholog functions as a P-loop ATPase rather than a protein kinase in the context of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; mutation is functionally complemented by human TP53RK
Visualize the interactome of BUD32
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.838 0.800 0.875
Vac/Vac Memb 0.163 0.122 0.089
Mito NaN 0.185 NaN
Cytoplasm NaN NaN 0.054

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 3020

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
BUD32 6 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family physical 11 7 6 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, PCA, Far Western, Biochemical Activity, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
CGI121 YML036W Component of the EKC/KEOPS complex physical 8 5 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Far Western, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase physical 8 4 6 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Two-hybrid, Biochemical Activity, Affinity Capture-Western, Biochemical Activity
RTN1 YDR233C Reticulon protein genetic 4 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SPA2 YLL021W Component of the polarisome genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GAS5 YOL030W 1,3-beta-glucanosyltransferase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 2 2 2 Affinity Capture-MS, Two-hybrid
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Affinity Capture-MS, Two-hybrid
IMD4 YML056C Inosine monophosphate dehydrogenase physical 2 2 2 Affinity Capture-MS, Two-hybrid
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 2 2 Dosage Growth Defect, Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 2 2 2 Dosage Growth Defect, Negative Genetic
PFU1 YDR306C F-box protein that regulates pheromone-dependent morphogenesis genetic 2 2 2 Dosage Growth Defect, Negative Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 2 1 2 Negative Genetic, Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 2 1 2 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 2 1 2 Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SCH9 YHR205W AGC family protein kinase physical 2 2 1 Affinity Capture-Western, Biochemical Activity
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator physical 1 1 1 Affinity Capture-MS
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Dosage Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
HEF3 YNL014W Translational elongation factor EF-3 physical 1 1 1 Affinity Capture-MS
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
SGO1 YOR073W Component of the spindle checkpoint physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Affinity Capture-MS
RNH202 YDR279W Ribonuclease H2 subunit physical 1 1 1 Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Affinity Capture-MS
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
YHR033W YHR033W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor physical 1 1 1 Affinity Capture-MS
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor genetic 1 1 1 Dosage Growth Defect
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 Two-hybrid
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase physical 1 1 1 Two-hybrid
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system physical 1 1 1 Two-hybrid
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Two-hybrid
GON7 YJL184W Component of the EKC/KEOPS protein complex physical 1 1 1 Affinity Capture-Western
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex physical 1 1 1 Two-hybrid
BUD32 YGR262C Protein kinase physical 1 1 1 Biochemical Activity
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Lethality
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
RRP46 YGR095C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Phenotypic Suppression
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Dosage Growth Defect
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Dosage Growth Defect
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Dosage Growth Defect
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Dosage Growth Defect
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Dosage Growth Defect
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Dosage Growth Defect
LIN1 YHR156C Non-essential component of U5 snRNP genetic 1 1 1 Dosage Growth Defect
YHR131C YHR131C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
UGO1 YDR470C Outer membrane component of the mitochondrial fusion machinery genetic 1 1 1 Dosage Growth Defect
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay genetic 1 1 1 Dosage Growth Defect
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 1 1 1 Dosage Growth Defect
HTB1 YDR224C Histone H2B genetic 1 1 1 Dosage Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Dosage Growth Defect
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Dosage Growth Defect
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Dosage Growth Defect
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Dosage Growth Defect
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation genetic 1 1 1 Dosage Growth Defect
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Dosage Growth Defect
SNX41 YDR425W Sorting nexin genetic 1 1 1 Dosage Growth Defect
MLC1 YGL106W Essential light chain for Myo1p genetic 1 1 1 Dosage Growth Defect
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Dosage Growth Defect
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Dosage Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Dosage Growth Defect
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Dosage Growth Defect
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Dosage Growth Defect
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Dosage Growth Defect
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
MAL32 YBR299W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ALE1 YOR175C Broad-specificity lysophospholipid acyltransferase genetic 1 1 1 Negative Genetic