COX19 |
YLL018C-A |
Protein required for cytochrome c oxidase assembly |
physical |
5 |
4 |
1 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Far Western, Reconstituted Complex |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
1 |
4 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SHY1 |
YGR112W |
Mitochondrial inner membrane protein required for complex IV assembly |
genetic |
2 |
2 |
1 |
Dosage Lethality, Synthetic Rescue |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
physical |
1 |
1 |
1 |
PCA |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
MRPL36 |
YBR122C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SDH4 |
YDR178W |
Membrane anchor subunit of succinate dehydrogenase (SDH) |
physical |
1 |
1 |
1 |
PCA |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
physical |
1 |
1 |
1 |
PCA |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
physical |
1 |
1 |
1 |
Proximity Label-MS |
MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Proximity Label-MS |
MRPL15 |
YLR312W-A |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Proximity Label-MS |
MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
physical |
1 |
1 |
1 |
Proximity Label-MS |
OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
physical |
1 |
1 |
1 |
Proximity Label-MS |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX14 |
YML129C |
Mitochondrial cytochrome c oxidase (complex IV) assembly factor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
COX15 |
YER141W |
Heme a synthase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CTT1 |
YGR088W |
Cytosolic catalase T |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CTA1 |
YDR256C |
Catalase A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET117 |
YER058W |
Assembly factor that couples heme a synthesis to complex IV assembly |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
COA2 |
YPL189C-A |
Cytochrome oxidase assembly factor |
genetic |
1 |
1 |
1 |
Dosage Lethality |
AFG1 |
YEL052W |
Protein that may act as a chaperone for cytochrome c oxidase subunits |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |