PIR1 |
YKL164C |
O-glycosylated protein required for cell wall stability |
genetic |
6 |
2 |
5 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CHS7 |
YHR142W |
Protein of unknown function |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, RNA-sequencing evidence |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
CIS3 |
YJL158C |
Mannose-containing glycoprotein constituent of the cell wall |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Lethality |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
SSD1 |
YDR293C |
Translational repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
northern blot evidence |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCM1 |
YMR043W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RLM1 |
YPL089C |
MADS-box transcription factor |
regulation |
1 |
1 |
1 |
northern blot evidence |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MSC2 |
YDR205W |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SMM1 |
YNR015W |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCL049C |
YCL049C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MXR1 |
YER042W |
Methionine-S-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNG1 |
YGR197C |
Protein involved in resistance to nitrosoguanidine and 6-azauracil |
genetic |
1 |
1 |
1 |
Negative Genetic |
OSH7 |
YHR001W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR112C |
YHR112C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFS1 |
YLR178C |
Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUT7 |
YLR283W |
Regulator of mitochondrial proline metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |