Standard name Systematic name Name description Description
MPP10 YJR002W Component of the SSU processome and 90S preribosome Component of the SSU processome and 90S preribosome; required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p
Visualize the interactome of MPP10
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MPP10 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
UTP10 YJL109C Nucleolar protein physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
UTP22 YGR090W Component of the small-subunit processome physical 7 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
UTP6 YDR449C Nucleolar protein physical 7 3 4 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western
IMP4 YNL075W Component of the SSU processome physical 7 3 4 Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western
IMP3 YHR148W Component of the SSU processome physical 7 4 3 Affinity Capture-Western, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
UTP7 YER082C Nucleolar protein physical 6 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
UTP25 YIL091C Nucleolar protein physical 6 3 4 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 6 3 3 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP14 YDL148C Nucleolar protein physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 4 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
UTP9 YHR196W Nucleolar protein physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RRP9 YPR137W Protein involved in pre-rRNA processing physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
HAS1 YMR290C ATP-dependent RNA helicase physical 3 2 1 Two-hybrid, Two-hybrid, Affinity Capture-Western
UTP15 YMR093W Nucleolar protein physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 2 2 2 Affinity Capture-Western, Two-hybrid
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EMG1 YLR186W Methyltransferase for rRNA physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 2 2 1 Two-hybrid, Affinity Capture-Western
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAD53 YPL153C DNA damage response kinase regulation 1 1 1 protein kinase assay evidence
ENP2 YGR145W Component of the SSU physical 1 1 1 Affinity Capture-Western
DIP2 YLR129W Nucleolar protein physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Affinity Capture-Western
CSL4 YNL232W Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
UTP13 YLR222C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-Western
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
PRP4 YPR178W Splicing factor physical 1 1 1 Affinity Capture-MS
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage physical 1 1 1 Two-hybrid
UTP23 YOR004W Component of the small subunit processome physical 1 1 1 Affinity Capture-Western
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome physical 1 1 1 Affinity Capture-MS
NOP15 YNL110C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RRP3 YHR065C Protein involved in rRNA processing physical 1 1 1 Affinity Capture-Western
ROK1 YGL171W RNA-dependent ATPase physical 1 1 1 Affinity Capture-Western
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
NIP100 YPL174C Large subunit of the dynactin complex physical 1 1 1 Two-hybrid
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor physical 1 1 1 Affinity Capture-Western
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
SGD1 YLR336C Essential nuclear protein physical 1 1 1 Two-hybrid
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
TRF5 YNL299W Non-canonical poly(A) polymerase physical 1 1 1 Affinity Capture-MS
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
REE1 YJL217W Cytoplasmic protein involved in the regulation of enolase (ENO1) genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
DBP8 YHR169W ATPase, putative RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-Western
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing physical 1 1 1 Affinity Capture-MS
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex genetic 1 1 1 Negative Genetic
AIR1 YIL079C Zinc knuckle protein physical 1 1 1 Affinity Capture-MS
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
FCF1 YDR339C PINc domain endonuclease physical 1 1 1 Affinity Capture-Western
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Two-hybrid
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Biochemical Activity
FAF1 YIL019W Protein required for pre-rRNA processing physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
HBS1 YKR084C GTPase with similarity to translation release factors genetic 1 1 1 Negative Genetic
BUD23 YCR047C Ribosome biogenesis factor physical 1 1 1 Co-fractionation
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic