Standard name Systematic name Name description Description
RBD2 YPL246C Possible rhomboid protease Possible rhomboid protease; has similarity to eukaryotic rhomboid proteases including Pcp1p
Visualize the interactome of RBD2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.113 NaN NaN
Golgi 0.270 0.760 0.443
Mito 0.748 0.623 0.922
Nucleolus 0.148 0.065 NaN
Cort. Patches NaN 0.188 NaN
Vac/Vac Memb NaN 0.104 0.054

GFP localization & abundance

GFP localization GFP abundance
Golgi, early Golgi 7850

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RBD2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RBD2 YPL246C Possible rhomboid protease physical 3 1 3 PCA, PCA, PCA
GET2 YER083C Subunit of the GET complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPA1 YER049W Prolyl hydroxylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 2 1 2 PCA, PCA
VAM7 YGL212W Vacuolar SNARE protein physical 2 1 2 Two-hybrid, Two-hybrid
YPT35 YHR105W Endosomal protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth physical 2 1 2 PCA, PCA
SDD2 YMR074C Protein with homology to human PDCD5 genetic 2 1 2 Negative Genetic, Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 2 1 2 Negative Genetic, Negative Genetic
GTT1 YIR038C ER associated glutathione S-transferase physical 2 1 2 PCA, PCA
CTR2 YHR175W Low-affinity copper transporter of the vacuolar membrane physical 2 1 2 PCA, PCA
ERS1 YCR075C Protein involved in cystine transport physical 2 1 2 PCA, PCA
LEE1 YPL054W Zinc-finger protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 1 1 Negative Genetic, Negative Genetic
AIM41 YOR215C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
FAA1 YOR317W Long chain fatty acyl-CoA synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
PGC1 YPL206C Phosphatidylglycerol phospholipase C genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 PCA
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Positive Genetic
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
LAS17 YOR181W Actin assembly factor physical 1 1 1 Two-hybrid
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Phenotypic Suppression
COG3 YER157W Essential component of the conserved oligomeric Golgi complex physical 1 1 1 PCA
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Phenotypic Suppression
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Phenotypic Suppression
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Two-hybrid
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 physical 1 1 1 PCA
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 PCA
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase physical 1 1 1 PCA
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
LPP1 YDR503C Lipid phosphate phosphatase physical 1 1 1 PCA
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase physical 1 1 1 Two-hybrid
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Two-hybrid
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Biochemical Activity
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Biochemical Activity
SNX3 YOR357C Sorting nexin for late-Golgi enzymes physical 1 1 1 Two-hybrid
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi physical 1 1 1 PCA
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 PCA
TVP15 YDR100W Integral membrane protein physical 1 1 1 PCA
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking physical 1 1 1 PCA
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 PCA
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 PCA
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 PCA
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 PCA
TVP38 YKR088C Integral membrane protein physical 1 1 1 PCA
YML018C YML018C Protein of unknown function physical 1 1 1 PCA
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 PCA
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) physical 1 1 1 PCA
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-RNA
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Positive Genetic
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
RPL15B YMR121C Ribosomal 60S subunit protein L15B genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex physical 1 1 1 PCA
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Lethality
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
CPT1 YNL130C Cholinephosphotransferase physical 1 1 1 PCA
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ERV41 YML067C Protein localized to COPII-coated vesicles physical 1 1 1 PCA
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 PCA
ERG25 YGR060W C-4 methyl sterol oxidase physical 1 1 1 PCA
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation physical 1 1 1 PCA
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase physical 1 1 1 PCA
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 1 1 1 PCA
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function physical 1 1 1 PCA
DOS2 YDR068W Protein of unknown function physical 1 1 1 PCA
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
MRX3 YBL095W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 Biochemical Activity
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles physical 1 1 1 PCA
BAP2 YBR068C High-affinity leucine permease physical 1 1 1 PCA
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic