Standard name Systematic name Name description Description
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress
Visualize the interactome of RGD2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.109 0.073 0.096
Cort. Patches 0.284 0.217 0.262
Cytoplasm 0.351 0.360 0.362
ER 0.102 0.207 0.058
Endosome 0.075 NaN 0.056
Golgi 0.057 0.115 NaN
Mito 0.219 0.137 0.058
Vac/Vac Memb 0.067 0.076 0.133
Budsite NaN NaN 0.054
SpindlePole NaN NaN 0.112

GFP localization & abundance

GFP localization GFP abundance
bud neck, cytoplasm, cell periphery 1750

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RGD2 0 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 2 1 2 Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
UBS1 YBR165W Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p genetic 2 1 2 Negative Genetic, Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
PIN2 YOR104W Exomer-dependent cargo protein physical 2 1 2 PCA, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Dosage Rescue
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Lethality
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase physical 1 1 1 Two-hybrid
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation genetic 1 1 1 Dosage Rescue
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 Two-hybrid
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 PCA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Positive Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
SWH1 YAR042W Protein similar to mammalian oxysterol-binding protein genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
YPR027C YPR027C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
NNK1 YKL171W Protein kinase physical 1 1 1 Two-hybrid
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-Western
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Positive Genetic
ASF2 YDL197C Anti-silencing protein genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Dosage Rescue
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p physical 1 1 1 PCA
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
AMD2 YDR242W Putative amidase genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic