Standard name Systematic name Name description Description
RPN14 YGL004C Evolutionarily conserved 19S regulatory particle assembly-chaperone Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p
Visualize the interactome of RPN14
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.948 0.974 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 2210

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RPN14 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 9 4 6 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Enhancement
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 8 3 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 8 5 5 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Co-crystal Structure
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 6 4 4 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 6 3 3 Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 5 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 5 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 4 4 4 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Reconstituted Complex
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 4 3 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
BIT2 YBR270C Subunit of TORC2 membrane-associated complex genetic 2 1 2 Negative Genetic, Negative Genetic
ECM29 YHL030W Scaffold protein genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity genetic 1 1 1 Phenotypic Suppression
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Rescue
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease physical 1 1 1 Affinity Capture-MS
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Dosage Rescue
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
GAL1 YBR020W Galactokinase genetic 1 1 1 Negative Genetic
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Negative Genetic