Standard name | Systematic name | Name description | Description |
---|---|---|---|
TGL5 | YOR081C | Bifunctional triacylglycerol lipase and LPA acyltransferase | Bifunctional triacylglycerol lipase and LPA acyltransferase; lipid particle-localized triacylglycerol (TAG) lipase involved in triacylglycerol mobilization; catalyzes acylation of lysophosphatidic acid (LPA); potential Cdc28p substrate; TGL5 has a paralog, TGL4, that arose from the whole genome duplication |
Cell cycle phase and timing of transcription peak
Cell cycle phase | Time (min) |
---|---|
G1(P) | 0 |
CYCLoPs localization & abundance
WT1 | WT2 | WT3 | |
---|---|---|---|
Endosome | 0.188 | 0.257 | 0.195 |
Mito | 0.591 | 0.611 | 0.289 |
Nucleolus | 0.182 | 0.126 | 0.055 |
Peroxisome | 0.330 | 0.192 | 0.172 |
SpindlePole | 0.267 | 0.174 | 0.547 |
Cytoplasm | NaN | NaN | 0.062 |
GFP localization & abundance
GFP localization | GFP abundance |
---|---|
no data | no data |
GO term count
Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
---|---|---|---|---|---|
TGL5 | 2 | 0 | 0 | 0 | 0 |
Enzyme information
Catalyzed reactions in Yeast8 |
---|
r_3282 (TAG lipase (1-16:0, 2-18:1, 3-18:0), lipid particle), r_3287 (TAG lipase (1-16:1, 2-18:1, 3-18:1), lipid particle), r_2341 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:1, 2-18:1), lipid particle), r_3268 (TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle), r_3292 (TAG lipase (1-18:1, 2-18:1, 3-16:0), lipid particle), r_3273 (TAG lipase (1-18:0, 2-16:1, 3-16:1), lipid particle), r_3278 (TAG lipase (1-18:1, 2-16:1, 3-18:0), lipid particle), r_3283 (TAG lipase (1-16:0, 2-18:1, 3-18:1), lipid particle), r_3264 (TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle), r_2342 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:0, 2-18:1), lipid particle), r_3288 (TAG lipase (1-18:0, 2-18:1, 3-16:0), lipid particle), r_3269 (TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle), r_3293 (TAG lipase (1-18:1, 2-18:1, 3-16:1), lipid particle), r_3274 (TAG lipase (1-18:0, 2-16:1, 3-18:0), lipid particle), r_3279 (TAG lipase (1-18:1, 2-16:1, 3-18:1), lipid particle), r_3284 (TAG lipase (1-16:1, 2-18:1, 3-16:0), lipid particle), r_2343 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-18:1, 2-18:1), lipid particle), r_3265 (TAG lipase (1-16:0, 2-16:1, 3-16:1), lipid particle), r_3289 (TAG lipase (1-18:0, 2-18:1, 3-16:1), lipid particle), r_3270 (TAG lipase (1-16:1, 2-16:1, 3-18:0), lipid particle), r_3294 (TAG lipase (1-18:1, 2-18:1, 3-18:0), lipid particle), r_3277 (TAG lipase (1-18:1, 2-16:1, 3-16:1), lipid particle), r_3275 (TAG lipase (1-18:0, 2-16:1, 3-18:1), lipid particle), r_3280 (TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle), r_3285 (TAG lipase (1-16:1, 2-18:1, 3-16:1), lipid particle), r_3266 (TAG lipase (1-16:0, 2-16:1, 3-18:0), lipid particle), r_3290 (TAG lipase (1-18:0, 2-18:1, 3-18:0), lipid particle), r_3271 (TAG lipase (1-16:1, 2-16:1, 3-18:1), lipid particle), r_3295 (TAG lipase (1-18:1, 2-18:1, 3-18:1), lipid particle), r_3276 (TAG lipase (1-18:1, 2-16:1, 3-16:0), lipid particle), r_3281 (TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle), r_3286 (TAG lipase (1-16:1, 2-18:1, 3-18:0), lipid particle), r_3291 (TAG lipase (1-18:0, 2-18:1, 3-18:1), lipid particle), r_2340 (1-acyl-sn-glycerol-3-phosphate acyltransferase (1-16:0, 2-18:1), lipid particle), r_3267 (TAG lipase (1-16:0, 2-16:1, 3-18:1), lipid particle), r_3272 (TAG lipase (1-18:0, 2-16:1, 3-16:0), lipid particle) |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
---|---|---|---|---|---|---|---|
FKH1 | YIL131C | Forkhead family transcription factor | regulation | 2 | 2 | 2 | chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CDC28 | YBR160W | Cyclin-dependent kinase (CDK) catalytic subunit | physical | 2 | 1 | 2 | Biochemical Activity, Biochemical Activity |
TPM2 | YIL138C | Minor isoform of tropomyosin | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
YKR075C | YKR075C | Protein of unknown function | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
CLN3 | YAL040C | G1 cyclin involved in cell cycle progression | genetic | 2 | 1 | 1 | Negative Genetic, Negative Genetic |
SFP1 | YLR403W | Regulates transcription of ribosomal protein and biogenesis genes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
SPT10 | YJL127C | Histone H3 acetylase with a role in transcriptional regulation | regulation | 1 | 1 | 1 | quantitative reverse transcription polymerase chain reaction evidence |
FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | ChEC-Seq experiments |
TFC7 | YOR110W | RNA pol III transcription initiation factor complex (TFIIIC) subunit | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
UGA3 | YDL170W | Transcriptional activator for GABA-dependent induction of GABA genes | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
CWC25 | YNL245C | Splicing factor required for the first step of pre-mRNA splicing | genetic | 1 | 1 | 1 | Positive Genetic |
GUS1 | YGL245W | Glutamyl-tRNA synthetase (GluRS) | physical | 1 | 1 | 1 | Affinity Capture-MS |
RPC82 | YPR190C | RNA polymerase III subunit C82 | genetic | 1 | 1 | 1 | Negative Genetic |
NAP1 | YKR048C | Histone chaperone and assembly chaperone for Rps6a/b | physical | 1 | 1 | 1 | Affinity Capture-MS |
NIP1 | YMR309C | eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) | physical | 1 | 1 | 1 | Affinity Capture-MS |
CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA |
NAB2 | YGL122C | Nuclear polyadenylated RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA |
ARC15 | YIL062C | Subunit of the ARP2/3 complex | genetic | 1 | 1 | 1 | Negative Genetic |
BMH2 | YDR099W | 14-3-3 protein, minor isoform | physical | 1 | 1 | 1 | Affinity Capture-MS |
GCN1 | YGL195W | Positive regulator of the Gcn2p kinase activity | physical | 1 | 1 | 1 | PCA |
GCD7 | YLR291C | Beta subunit of translation initiation factor eIF2B | physical | 1 | 1 | 1 | PCA |
DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA |
ISW1 | YBR245C | ATPase subunit of imitation-switch (ISWI) class chromatin remodelers | physical | 1 | 1 | 1 | Affinity Capture-RNA |
END3 | YNL084C | EH domain-containing protein involved in endocytosis | genetic | 1 | 1 | 1 | Negative Genetic |
HMO1 | YDR174W | Chromatin associated high mobility group (HMG) family member | genetic | 1 | 1 | 1 | Negative Genetic |
ILV1 | YER086W | Threonine deaminase, catalyzes first step in isoleucine biosynthesis | genetic | 1 | 1 | 1 | Negative Genetic |
RAV1 | YJR033C | Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) | genetic | 1 | 1 | 1 | Negative Genetic |
DRS2 | YAL026C | Trans-golgi network aminophospholipid translocase (flippase) | genetic | 1 | 1 | 1 | Negative Genetic |
HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA |
SSZ1 | YHR064C | Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) | physical | 1 | 1 | 1 | Affinity Capture-MS |
BBC1 | YJL020C | Protein possibly involved in assembly of actin patches | physical | 1 | 1 | 1 | Two-hybrid |
PPQ1 | YPL179W | Protein phosphatase that regulates the mating response | genetic | 1 | 1 | 1 | Negative Genetic |
EAP1 | YKL204W | eIF4E-associated protein, competes with eIF4G for binding to eIF4E | genetic | 1 | 1 | 1 | Positive Genetic |
BIM1 | YER016W | Microtubule plus end-tracking protein | genetic | 1 | 1 | 1 | Negative Genetic |
MOB2 | YFL034C-B | Activator of Cbk1p kinase | genetic | 1 | 1 | 1 | Negative Genetic |
MHT1 | YLL062C | S-methylmethionine-homocysteine methyltransferase | physical | 1 | 1 | 1 | PCA |
SSC1 | YJR045C | Hsp70 family ATPase | physical | 1 | 1 | 1 | Affinity Capture-MS |
KAR3 | YPR141C | Minus-end-directed microtubule motor | genetic | 1 | 1 | 1 | Negative Genetic |
PET111 | YMR257C | Mitochondrial translational activator specific for the COX2 mRNA | genetic | 1 | 1 | 1 | Negative Genetic |
RAP1 | YNL216W | Essential DNA-binding transcription regulator that binds many loci | genetic | 1 | 1 | 1 | Negative Genetic |
KAR2 | YJL034W | ATPase involved in protein import into the ER | physical | 1 | 1 | 1 | Affinity Capture-MS |
OST4 | YDL232W | Subunit of the oligosaccharyltransferase complex of the ER lumen | genetic | 1 | 1 | 1 | Negative Genetic |
HFM1 | YGL251C | Meiosis specific DNA helicase | genetic | 1 | 1 | 1 | Negative Genetic |
SPO74 | YGL170C | Component of the meiotic outer plaque of the spindle pole body | genetic | 1 | 1 | 1 | Negative Genetic |
CLB3 | YDL155W | B-type cyclin involved in cell cycle progression | physical | 1 | 1 | 1 | Affinity Capture-MS |
SSB2 | YNL209W | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone | physical | 1 | 1 | 1 | Affinity Capture-MS |
RPL40A | YIL148W | Ubiquitin-ribosomal 60S subunit protein L40A fusion protein | physical | 1 | 1 | 1 | Affinity Capture-MS |
HXK1 | YFR053C | Hexokinase isoenzyme 1 | physical | 1 | 1 | 1 | Affinity Capture-MS |
GLO2 | YDR272W | Cytoplasmic glyoxalase II | physical | 1 | 1 | 1 | Affinity Capture-MS |
ZUO1 | YGR285C | Ribosome-associated chaperone | physical | 1 | 1 | 1 | Affinity Capture-MS |
YEF3 | YLR249W | Translation elongation factor 3 | physical | 1 | 1 | 1 | Affinity Capture-MS |
TPD3 | YAL016W | Regulatory subunit A of the heterotrimeric PP2A complex | physical | 1 | 1 | 1 | PCA |
TGL5 | YOR081C | Bifunctional triacylglycerol lipase and LPA acyltransferase | physical | 1 | 1 | 1 | PCA |
VAM6 | YDL077C | Guanine nucleotide exchange factor for the GTPase Gtr1p | physical | 1 | 1 | 1 | Affinity Capture-MS |
TMA64 | YDR117C | Protein of unknown function that associates with ribosomes | genetic | 1 | 1 | 1 | Positive Genetic |
UTP8 | YGR128C | Nucleolar protein required for export of tRNAs from the nucleus | genetic | 1 | 1 | 1 | Negative Genetic |
YLR012C | YLR012C | Putative protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic |
YAR029W | YAR029W | Member of DUP240 gene family but contains no transmembrane domains | genetic | 1 | 1 | 1 | Negative Genetic |
XRN1 | YGL173C | Evolutionarily-conserved 5'-3' exonuclease | genetic | 1 | 1 | 1 | Negative Genetic |
SHM2 | YLR058C | Cytosolic serine hydroxymethyltransferase | physical | 1 | 1 | 1 | Affinity Capture-MS |
OSM1 | YJR051W | Fumarate reductase, catalyzes the reduction of fumarate to succinate | genetic | 1 | 1 | 1 | Negative Genetic |
APJ1 | YNL077W | Hsp40 chaperone with a role in SUMO-mediated protein degradation | physical | 1 | 1 | 1 | Affinity Capture-MS |
DGA1 | YOR245C | Diacylglycerol acyltransferase | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
SDD4 | YPR022C | Putative transcription factor, as suggested by computational analysis | genetic | 1 | 1 | 1 | Negative Genetic |
SCS7 | YMR272C | Sphingolipid alpha-hydroxylase | physical | 1 | 1 | 1 | PCA |
SWS2 | YNL081C | Putative mitochondrial ribosomal protein of the small subunit | genetic | 1 | 1 | 1 | Negative Genetic |
CMC2 | YBL059C-A | Protein involved in respiratory chain complex assembly or maintenance | genetic | 1 | 1 | 1 | Negative Genetic |
RPL21B | YPL079W | Ribosomal 60S subunit protein L21B | genetic | 1 | 1 | 1 | Negative Genetic |
SHC1 | YER096W | Sporulation-specific activator of Chs3p (chitin synthase III) | genetic | 1 | 1 | 1 | Negative Genetic |
SEC12 | YNR026C | Guanine nucleotide exchange factor (GEF) | genetic | 1 | 1 | 1 | Positive Genetic |
RMD9 | YGL107C | Mitochondrial protein that controls mitochondrial gene expression | genetic | 1 | 1 | 1 | Negative Genetic |
ROF1 | YHR177W | Putative transcription factor containing a WOPR domain | genetic | 1 | 1 | 1 | Positive Genetic |