| Standard name | Systematic name | Name description | Description |
|---|---|---|---|
| DGA1 | YOR245C | Diacylglycerol acyltransferase | Diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor; Lro1p and Dga1p can O-acylate ceramides; localized to lipid particles |
Cell cycle phase and timing of transcription peak
| Cell cycle phase | Time (min) |
|---|---|
CYCLoPs localization & abundance
| WT1 | WT2 | WT3 | |
|---|---|---|---|
| Cell Periphery | 0.076 | NaN | NaN |
| Cytoplasm | 0.590 | 0.574 | 0.581 |
| ER | 0.229 | 0.396 | 0.324 |
| Mito | 0.146 | NaN | NaN |
GFP localization & abundance
| GFP localization | GFP abundance |
|---|---|
| ER, cytoplasm | 907 |
GO term count
| Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
|---|---|---|---|---|---|
| DGA1 | 4 | 0 | 0 | 0 | 0 |
Enzyme information
| Catalyzed reactions in Yeast8 |
|---|
| r_2414 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), lipid particle), r_2407 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), lipid particle), r_2387 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), ER membrane), r_2374 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), ER membrane), r_2422 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:0), lipid particle), r_2415 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), lipid particle), r_2368 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), ER membrane), r_2408 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), lipid particle), r_2388 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), ER membrane), r_2375 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:0), ER membrane), r_2369 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:0), ER membrane), r_2423 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:0), lipid particle), r_2416 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), lipid particle), r_2409 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), lipid particle), r_2389 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), ER membrane), r_2376 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:1), ER membrane), r_2424 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:1), lipid particle), r_2417 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), lipid particle), r_2410 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), lipid particle), r_2390 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:0), ER membrane), r_2370 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:0), ER membrane), r_2377 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:1), ER membrane), r_2425 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), lipid particle), r_2371 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:0), ER membrane), r_2418 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), lipid particle), r_2411 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), lipid particle), r_2391 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:0), ER membrane), r_2378 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:1), ER membrane), r_2426 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:1), lipid particle), r_2419 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:0), lipid particle), r_2372 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:0), ER membrane), r_2412 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), lipid particle), r_2392 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:1), ER membrane), r_2379 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:1), ER membrane), r_2427 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:1), lipid particle), r_2420 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:0), lipid particle), r_2373 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:0), ER membrane), r_2413 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), lipid particle), r_2393 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:1), ER membrane), r_2380 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:1), ER membrane), r_2428 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), lipid particle), r_2421 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:0), lipid particle), r_2400 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-16:0), lipid particle), r_2429 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), lipid particle), r_2394 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:1), ER membrane), r_2381 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:1), ER membrane), r_2401 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-16:0), lipid particle), r_2430 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), lipid particle), r_2395 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-18:1), ER membrane), r_2382 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:1), ER membrane), r_2402 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-16:0), lipid particle), r_2431 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), lipid particle), r_2396 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-18:1), ER membrane), r_2383 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-16:1), ER membrane), r_2403 (diacylglycerol acyltransferase (1-16:1, 2-18:1, 3-16:0), lipid particle), r_2397 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-18:1), ER membrane), r_2384 (diacylglycerol acyltransferase (1-16:0, 2-16:1, 3-18:0), ER membrane), r_2404 (diacylglycerol acyltransferase (1-18:0, 2-16:1, 3-16:0), lipid particle), r_2398 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-18:1), ER membrane), r_2385 (diacylglycerol acyltransferase (1-16:0, 2-18:1, 3-18:0), ER membrane), r_2405 (diacylglycerol acyltransferase (1-18:0, 2-18:1, 3-16:0), lipid particle), r_2399 (diacylglycerol acyltransferase (1-18:1, 2-18:1, 3-18:1), ER membrane), r_2386 (diacylglycerol acyltransferase (1-16:1, 2-16:1, 3-18:0), ER membrane), r_2406 (diacylglycerol acyltransferase (1-18:1, 2-16:1, 3-16:0), lipid particle) |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.| Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
|---|---|---|---|---|---|---|---|
| LRO1 | YNR008W | Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) | genetic | 15 | 4 | 12 | Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
| ARE2 | YNR019W | Acyl-CoA:sterol acyltransferase | genetic | 12 | 4 | 9 | Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement |
| ARE1 | YCR048W | Acyl-CoA:sterol acyltransferase | genetic | 12 | 4 | 9 | Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement |
| DGK1 | YOR311C | Diacylglycerol kinase | genetic | 7 | 3 | 5 | Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression |
| GET2 | YER083C | Subunit of the GET complex | genetic | 4 | 2 | 3 | Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic |
| ICE2 | YIL090W | Integral ER membrane protein with type-III transmembrane domains | genetic | 4 | 2 | 3 | Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement |
| BFR1 | YOR198C | Component of mRNP complexes associated with polyribosomes | genetic | 3 | 2 | 2 | Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| DOP1 | YDR141C | Protein involved in vesicular transport at trans-Golgi network (TGN) | genetic | 3 | 2 | 2 | Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| TSC3 | YBR058C-A | Protein that stimulates the activity of serine palmitoyltransferase | genetic | 3 | 2 | 2 | Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| RDL1 | YOR285W | Thiosulfate sulfurtransferase | genetic | 3 | 2 | 2 | Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| OLE1 | YGL055W | Delta(9) fatty acid desaturase | genetic | 3 | 2 | 2 | Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| PAH1 | YMR165C | Mg2+-dependent phosphatidate (PA) phosphatase | genetic | 3 | 2 | 2 | Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement |
| PMA1 | YGL008C | Plasma membrane P2-type H+-ATPase | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic |
| PHO23 | YNL097C | Component of the Rpd3L histone deacetylase complex | genetic | 3 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic |
| SNF2 | YOR290C | Catalytic subunit of the SWI/SNF chromatin remodeling complex | genetic | 2 | 2 | 2 | Phenotypic Enhancement, Phenotypic Suppression |
| FKH1 | YIL131C | Forkhead family transcription factor | regulation | 2 | 1 | 2 | chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| RPP1A | YDL081C | Ribosomal stalk protein P1 alpha | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
| SNF4 | YGL115W | Activating gamma subunit of the AMP-activated Snf1p kinase complex | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
| MTC4 | YBR255W | Protein of unknown function | genetic | 2 | 1 | 1 | Positive Genetic, Positive Genetic |
| SFP1 | YLR403W | Regulates transcription of ribosomal protein and biogenesis genes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| SPT10 | YJL127C | Histone H3 acetylase with a role in transcriptional regulation | regulation | 1 | 1 | 1 | quantitative reverse transcription polymerase chain reaction evidence |
| SUA7 | YPR086W | Transcription factor TFIIB | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| COG3 | YER157W | Essential component of the conserved oligomeric Golgi complex | genetic | 1 | 1 | 1 | Negative Genetic |
| CAF20 | YOR276W | Phosphoprotein of the mRNA cap-binding complex | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| COG4 | YPR105C | Essential component of the conserved oligomeric Golgi complex | genetic | 1 | 1 | 1 | Negative Genetic |
| DAL81 | YIR023W | Positive regulator of genes in multiple nitrogen degradation pathways | genetic | 1 | 1 | 1 | Negative Genetic |
| BFR1 | YOR198C | Component of mRNP complexes associated with polyribosomes | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| CSG2 | YBR036C | Endoplasmic reticulum membrane protein | genetic | 1 | 1 | 1 | Negative Genetic |
| CHS5 | YLR330W | Component of the exomer complex | genetic | 1 | 1 | 1 | Negative Genetic |
| BRL1 | YHR036W | Essential nuclear envelope/ER integral membrane protein | genetic | 1 | 1 | 1 | Synthetic Lethality |
| ATG32 | YIL146C | Mitochondrial outer membrane protein required to initiate mitophagy | genetic | 1 | 1 | 1 | Negative Genetic |
| CAB4 | YGR277C | Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) | genetic | 1 | 1 | 1 | Negative Genetic |
| KSS1 | YGR040W | Mitogen-activated protein kinase (MAPK) | physical | 1 | 1 | 1 | Biochemical Activity |
| HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| UBX2 | YML013W | Bridging factor involved in ER-associated protein degradation (ERAD) | physical | 1 | 1 | 1 | Affinity Capture-Western |
| SSB1 | YDL229W | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone | physical | 1 | 1 | 1 | Affinity Capture-MS |
| VAM6 | YDL077C | Guanine nucleotide exchange factor for the GTPase Gtr1p | physical | 1 | 1 | 1 | Affinity Capture-MS |
| PUF3 | YLL013C | Protein of the mitochondrial outer surface | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| MPS3 | YJL019W | Nuclear envelope protein | physical | 1 | 1 | 1 | Affinity Capture-MS |
| SEC61 | YLR378C | Conserved ER protein translocation channel | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPT2 | YDL007W | ATPase of the 19S regulatory particle of the 26S proteasome | genetic | 1 | 1 | 1 | Negative Genetic |
| PRB1 | YEL060C | Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity | genetic | 1 | 1 | 1 | Negative Genetic |
| HSP60 | YLR259C | Tetradecameric mitochondrial chaperonin | genetic | 1 | 1 | 1 | Negative Genetic |
| RIA1 | YNL163C | Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis | genetic | 1 | 1 | 1 | Negative Genetic |
| TEP1 | YNL128W | PTEN homolog with no demonstrated inositol lipid phosphatase activity | genetic | 1 | 1 | 1 | Negative Genetic |
| YJU3 | YKL094W | Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| GRS2 | YPR081C | Glycine-tRNA synthetase, not expressed under normal growth conditions | genetic | 1 | 1 | 1 | Negative Genetic |
| UGP1 | YKL035W | UDP-glucose pyrophosphorylase (UGPase) | genetic | 1 | 1 | 1 | Negative Genetic |
| EAF7 | YNL136W | Subunit of the NuA4 histone acetyltransferase complex | genetic | 1 | 1 | 1 | Dosage Growth Defect |
| YDJ1 | YNL064C | Type I HSP40 co-chaperone | genetic | 1 | 1 | 1 | Positive Genetic |
| VPS27 | YNR006W | Endosomal protein that forms a complex with Hse1p | genetic | 1 | 1 | 1 | Negative Genetic |
| TGL5 | YOR081C | Bifunctional triacylglycerol lipase and LPA acyltransferase | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| TGL3 | YMR313C | Bifunctional triacylglycerol lipase and LPE acyltransferase | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| YJR084W | YJR084W | Protein that forms a complex with Thp3p | genetic | 1 | 1 | 1 | Positive Genetic |
| TLG1 | YDR468C | Essential t-SNARE that mediates fusion of vesicles with the late Golgi | genetic | 1 | 1 | 1 | Negative Genetic |
| HYP2 | YEL034W | Translation elongation factor eIF-5A | genetic | 1 | 1 | 1 | Negative Genetic |
| PSF2 | YJL072C | Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) | genetic | 1 | 1 | 1 | Negative Genetic |
| YKT6 | YKL196C | Vesicle membrane protein (v-SNARE) with acyltransferase activity | genetic | 1 | 1 | 1 | Negative Genetic |
| TIF34 | YMR146C | eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) | genetic | 1 | 1 | 1 | Negative Genetic |
| TVP38 | YKR088C | Integral membrane protein | genetic | 1 | 1 | 1 | Negative Genetic |
| PCT1 | YGR202C | Cholinephosphate cytidylyltransferase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| TOR1 | YJR066W | PIK-related protein kinase and rapamycin target | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| UBC12 | YLR306W | Enzyme that mediates the conjugation of Rub1p | genetic | 1 | 1 | 1 | Negative Genetic |
| RRG9 | YNL213C | Protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic |
| VAM7 | YGL212W | Vacuolar SNARE protein | genetic | 1 | 1 | 1 | Negative Genetic |
| YPL039W | YPL039W | Putative protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic |
| STT4 | YLR305C | Phosphatidylinositol-4-kinase | genetic | 1 | 1 | 1 | Negative Genetic |
| MTC1 | YJL123C | Protein of unknown function that may interact with ribosomes | genetic | 1 | 1 | 1 | Negative Genetic |
| MDY2 | YOL111C | Protein involved in inserting tail-anchored proteins into ER membranes | genetic | 1 | 1 | 1 | Negative Genetic |
| PEX30 | YLR324W | ER-resident protein involved in peroxisomal biogenesis | genetic | 1 | 1 | 1 | Synthetic Rescue |
| SEI1 | YLR404W | Seipin involved in lipid droplet (LD) assembly | genetic | 1 | 1 | 1 | Synthetic Rescue |
| LDB16 | YCL005W | Protein involved in lipid droplet (LD) assembly | genetic | 1 | 1 | 1 | Synthetic Rescue |
| RIM13 | YMR154C | Calpain-like cysteine protease | genetic | 1 | 1 | 1 | Synthetic Rescue |
| HRQ1 | YDR291W | 3'-5' DNA helicase of the conserved RecQ family | genetic | 1 | 1 | 1 | Positive Genetic |
| SGS1 | YMR190C | RecQ family nucleolar DNA helicase | genetic | 1 | 1 | 1 | Positive Genetic |
| NUP116 | YMR047C | FG-nucleoporin component of central core of the nuclear pore complex | genetic | 1 | 1 | 1 | Synthetic Growth Defect |
| MDM1 | YML104C | PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| NVJ1 | YHR195W | Nuclear envelope protein | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
| OPI1 | YHL020C | Transcriptional regulator of a variety of genes | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| SLC1 | YDL052C | 1-acyl-sn-glycerol-3-phosphate acyltransferase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| FAA1 | YOR317W | Long chain fatty acyl-CoA synthetase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| FAA4 | YMR246W | Long chain fatty acyl-CoA synthetase | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| CHO2 | YGR157W | Phosphatidylethanolamine methyltransferase (PEMT) | genetic | 1 | 1 | 1 | Synthetic Lethality |
| CDS1 | YBR029C | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) | genetic | 1 | 1 | 1 | Phenotypic Suppression |
| BRR6 | YGL247W | Essential nuclear envelope integral membrane protein | genetic | 1 | 1 | 1 | Synthetic Lethality |