| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
physical |
6 |
3 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Biochemical Activity, Biochemical Activity |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Phenotypic Enhancement |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FUN14 |
YAL008W |
Integral mitochondrial outer membrane (MOM) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| ADH4 |
YGL256W |
Alcohol dehydrogenase isoenzyme type IV |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| PUT3 |
YKL015W |
Transcriptional activator |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| SRO77 |
YBL106C |
Protein with roles in exocytosis and cation homeostasis |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| TVP23 |
YDR084C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| TPC1 |
YGR096W |
Mitochondrial membrane transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| YSC83 |
YHR017W |
Non-essential mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| MPC2 |
YHR162W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| YIL055C |
YIL055C |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| SET4 |
YJL105W |
Chromatin-associated protein involved in control of stress response |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| FOL1 |
YNL256W |
Multifunctional enzyme of the folic acid biosynthesis pathway |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| IRR1 |
YIL026C |
Subunit of the cohesin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR034C-A |
YOR034C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLO1 |
YAR050W |
Lectin-like protein involved in flocculation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GMC2 |
YLR445W |
Protein involved in meiotic crossing over |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
