Standard name Systematic name Name description Description
MET31 YPL038W Zinc-finger DNA-binding transcription factor Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication
Visualize the interactome of MET31
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.368 0.298 0.459
ER 0.079 NaN NaN
Mito 0.395 0.124 NaN
Nucleus 0.184 0.484 0.295
Vac/Vac Memb 0.184 0.205 0.230

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 521

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MET31 8 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 11 3 9 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 2 1 2 Negative Genetic, Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 2 1 2 Negative Genetic, Negative Genetic
MET4 YNL103W Leucine-zipper transcriptional activator physical 2 2 1 Two-hybrid, Reconstituted Complex
INO2 YDR123C Transcription factor genetic 2 1 1 Negative Genetic, Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET16 YPR167C 3'-phosphoadenylsulfate reductase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET6 YER091C Cobalamin-independent methionine synthase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AAR2 YBL074C Component of the U5 snRNP complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYS3 YAL012W Cystathionine gamma-lyase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOP4 YJL192C ER-membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET2 YNL277W L-homoserine-O-acetyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STR3 YGL184C Peroxisomal cystathionine beta-lyase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YNL277W-A YNL277W-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YDR042C YDR042C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SAM1 YLR180W S-adenosylmethionine synthetase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CSN9 YDR179C Subunit of the Cop9 signalosome regulation 1 1 1 DNA to cDNA expression microarray evidence
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET5 YJR137C Sulfite reductase beta subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Positive Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Two-hybrid
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Positive Genetic
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 1 1 1 Two-hybrid
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Two-hybrid
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Two-hybrid
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Two-hybrid
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif physical 1 1 1 Affinity Capture-MS
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Synthetic Rescue
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
LSB1 YGR136W Negative regulator of actin nucleation-promoting factor activity physical 1 1 1 Two-hybrid
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Two-hybrid
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
AMA1 YGR225W Activator of meiotic anaphase promoting complex (APC/C) genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
MET4 YNL103W Leucine-zipper transcriptional activator genetic 1 1 1 Synthetic Rescue
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
MYO3 YKL129C One of two type I myosins physical 1 1 1 Two-hybrid
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Two-hybrid
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 Two-hybrid
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
RGI2 YIL057C Protein of unknown function genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Positive Genetic
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 1 1 1 Two-hybrid
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring physical 1 1 1 Two-hybrid
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family genetic 1 1 1 Negative Genetic