Standard name Systematic name Name description Description
MRS1 YIR021W Splicing protein Splicing protein; required for splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA; MRS1 has a paralog, CCE1, that arose from the whole genome duplication
Visualize the interactome of MRS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.943 0.838 0.430
Cytoplasm NaN 0.131 0.243
ER NaN 0.050 0.065
Vac/Vac Memb NaN 0.094 NaN
Bud NaN NaN 0.093
Cort. Patches NaN NaN 0.131
SpindlePole NaN NaN 0.140

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 5240

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MRS1 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
MRS1 YIR021W Splicing protein physical 2 1 2 Reconstituted Complex, Reconstituted Complex
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 2 Negative Genetic, Negative Genetic
BI3 Q0115 Mitochondrial mRNA maturase physical 2 1 2 Protein-RNA, Protein-RNA
SUV3 YPL029W ATP-dependent RNA helicase genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
CBP2 YHL038C Required for splicing of the group I intron bI5 of the COB pre-mRNA physical 2 1 1 Proximity Label-MS, Proximity Label-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Co-fractionation
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Proximity Label-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Proximity Label-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 1 1 1 Negative Genetic
ECM19 YLR390W Protein of unknown function genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RPL42A YNL162W Ribosomal 60S subunit protein L42A physical 1 1 1 Affinity Capture-MS
SPE2 YOL052C S-adenosylmethionine decarboxylase physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron physical 1 1 1 Proximity Label-MS
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Dosage Rescue
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression physical 1 1 1 Proximity Label-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Positive Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Positive Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Positive Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
RDL1 YOR285W Thiosulfate sulfurtransferase genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
BI3 Q0115 Mitochondrial mRNA maturase genetic 1 1 1 Synthetic Rescue
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
AIM34 YMR003W Protein of unknown function genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA physical 1 1 1 Proximity Label-MS
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Dosage Rescue