| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
1 |
4 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BIL2 |
YGL015C |
Formin inhibitor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM31 |
YBR176W |
Ketopantoate hydroxymethyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPB2 |
YAL056W |
Multistep regulator of cAMP-PKA signaling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IRC20 |
YLR247C |
E3 ubiquitin ligase and putative helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SCS22 |
YBL091C-A |
Protein involved in regulation of phospholipid metabolism |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD16 |
YBR114W |
Nucleotide excision repair (NER) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YKL162C |
YKL162C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RGT1 |
YKL038W |
Glucose-responsive transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SYT1 |
YPR095C |
Guanine nucleotide exchange factor (GEF) for Arf proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM32 |
YER176W |
DNA dependent ATPase/DNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INA1 |
YLR413W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX2 |
Q0250 |
Subunit II of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX3 |
Q0275 |
Subunit III of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDA1 |
YLR307W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO1 |
YJL196C |
Elongase I, medium-chain acyl elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR120W |
YJR120W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC13 |
YDR092W |
E2 ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMS1 |
YDR105C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKR018C |
YKR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF3 |
YLR034C |
Putative divalent metal ion transporter involved in iron homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML096W |
YML096W |
Putative protein with similarity to asparagine synthetases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIO5 |
YNR056C |
Putative transmembrane protein involved in the biotin biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMT6 |
YLR063W |
Methyltransferase required for m3U2843 methylation of the 25S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLO50 |
YLR049C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
