| UTP22 | YGR090W | Component of the small-subunit processome | physical | 11 | 4 | 8 | Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western | 
            
                | CKA1 | YIL035C | Alpha catalytic subunit of casein kinase 2 (CK2) | physical | 4 | 2 | 4 | Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid | 
            
                | IFH1 | YLR223C | Coactivator, regulates transcription of ribosomal protein (RP) genes | physical | 4 | 3 | 2 | Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid | 
            
                | PWP2 | YCR057C | Conserved 90S pre-ribosomal component | physical | 3 | 2 | 2 | Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS | 
            
                | FKH1 | YIL131C | Forkhead family transcription factor | regulation | 2 | 1 | 2 | chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence | 
            
                | UTP10 | YJL109C | Nucleolar protein | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | UTP4 | YDR324C | Subunit of U3-containing 90S preribosome and SSU processome complexes | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | ECM16 | YMR128W | Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | NOC4 | YPR144C | Nucleolar protein | physical | 2 | 1 | 2 | Affinity Capture-MS, Affinity Capture-MS | 
            
                | SFP1 | YLR403W | Regulates transcription of ribosomal protein and biogenesis genes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | ABF1 | YKL112W | DNA binding protein with possible chromatin-reorganizing activity | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | MED4 | YOR174W | Subunit of the RNA polymerase II mediator complex | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | CST6 | YIL036W | Basic leucine zipper (bZIP) transcription factor from ATF/CREB family | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | CBF5 | YLR175W | Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CKB1 | YGL019W | Beta regulatory subunit of casein kinase 2 (CK2) | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | CKB2 | YOR039W | Beta' regulatory subunit of casein kinase 2 (CK2) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BFR2 | YDR299W | Component of the SSU and 90S preribosomes | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | ENP2 | YGR145W | Component of the SSU | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | ESA1 | YOR244W | Catalytic subunit of the histone acetyltransferase complex (NuA4) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | NOP9 | YJL010C | Essential subunit of U3-containing 90S preribosome | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RIC1 | YLR039C | Protein involved in retrograde transport to the cis-Golgi network | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | NAN1 | YPL126W | U3 snoRNP protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DIP2 | YLR129W | Nucleolar protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UBP10 | YNL186W | Ubiquitin-specific protease, deubiquitinates Ub-protein moieties | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RVS167 | YDR388W | Calmodulin-binding actin-associated protein | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SHO1 | YER118C | Transmembrane osmosensor for filamentous growth and HOG pathways | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SLA1 | YBL007C | Cytoskeletal protein binding protein | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SPB4 | YFL002C | Putative ATP-dependent RNA helicase | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | YEF3 | YLR249W | Translation elongation factor 3 | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP21 | YLR409C | Subunit of U3-containing 90S preribosome and SSU processome complexes | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP13 | YLR222C | Nucleolar protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP8 | YGR128C | Nucleolar protein required for export of tRNAs from the nucleus | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RRP9 | YPR137W | Protein involved in pre-rRNA processing | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SSB1 | YDL229W | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP7 | YER082C | Nucleolar protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | TEF1 | YPR080W | Translational elongation factor EF-1 alpha | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP9 | YHR196W | Nucleolar protein | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | SBP1 | YHL034C | Protein that binds eIF4G and has a role in repression of translation | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | VAM6 | YDL077C | Guanine nucleotide exchange factor for the GTPase Gtr1p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP23 | YOR004W | Component of the small subunit processome | physical | 1 | 1 | 1 | Reconstituted Complex | 
            
                | UTP14 | YML093W | Subunit of U3-containing Small Subunit (SSU) processome complex | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | UTP18 | YJL069C | Small-subunit processome protein involved in pre-18S rRNA maturation | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | RRP7 | YCL031C | Essential protein involved in rRNA processing and ribosome biogenesis | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | RTT103 | YDR289C | Protein involved in transcription termination by RNA polymerase II | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YRA1 | YDR381W | Nuclear polyadenylated RNA-binding protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TRM9 | YML014W | tRNA methyltransferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | THP3 | YPR045C | Protein that may have a role in transcription elongation | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UTP30 | YKR060W | Subunit of U3-containing 90S preribosome complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SKI2 | YLR398C | Ski complex component and putative RNA helicase | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | TSR3 | YOR006C | Protein required for 20S pre-rRNA processing | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | SKI7 | YOR076C | GTP-binding protein that couples the Ski complex and exosome | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | TGS1 | YPL157W | Trimethyl guanosine synthase, conserved nucleolar methyl transferase | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | TSR2 | YLR435W | Protein with a potential role in pre-rRNA processing | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | TEL2 | YGR099W | Subunit of the ASTRA complex, involved in chromatin remodeling | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SUR1 | YPL057C | Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MRT4 | YKL009W | Protein involved in mRNA turnover and ribosome assembly | physical | 1 | 1 | 1 | Affinity Capture-Western | 
            
                | MRT4 | YKL009W | Protein involved in mRNA turnover and ribosome assembly | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | RRP5 | YMR229C | RNA binding protein involved in synthesis of 18S and 5.8S rRNAs | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RAT1 | YOR048C | Nuclear 5' to 3' single-stranded RNA exonuclease | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | NOP1 | YDL014W | Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CSL4 | YNL232W | Exosome non-catalytic core component | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RRP6 | YOR001W | Nuclear exosome exonuclease component | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RRP6 | YOR001W | Nuclear exosome exonuclease component | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | NOP12 | YOL041C | Nucleolar protein involved in pre-25S rRNA processing | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | HCR1 | YLR192C | eIF3j component of translation initiation factor 3 (eIF3) | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | NAB2 | YGL122C | Nuclear polyadenylated RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | NAM7 | YMR080C | ATP-dependent RNA helicase of the SFI superfamily | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | RCL1 | YOL010W | Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | BEM1 | YBR200W | Protein containing SH3-domains | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | ASC1 | YMR116C | G-protein beta subunit and guanine dissociation inhibitor for Gpa2p | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | BUD14 | YAR014C | Protein involved in bud-site selection | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | CTK1 | YKL139W | Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ENP1 | YBR247C | Protein associated with U3 and U14 snoRNAs | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | KRE33 | YNL132W | Acetyltransferase required for biogenesis of small ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | MRD1 | YPR112C | Essential conserved small ribosomal subunit (40s) synthesis factor | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | KRR1 | YCL059C | Nucleolar protein required for rRNA synthesis and ribosomal assembly | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CRM1 | YGR218W | Nuclear export factor, exportin | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | BUD21 | YOR078W | Component of small ribosomal subunit (SSU) processosome | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | NOP14 | YDL148C | Nucleolar protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GCN20 | YFR009W | Positive regulator of the Gcn2p kinase activity | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PCI8 | YIL071C | Possible shared subunit of Cop9 signalosome (CSN) and eIF3 | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CDC25 | YLR310C | Membrane bound guanine nucleotide exchange factor | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | BZZ1 | YHR114W | SH3 domain protein implicated in regulating actin polymerization | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | LSB3 | YFR024C-A | Protein containing a C-terminal SH3 domain | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | MLP1 | YKR095W | Myosin-like protein associated with the nuclear envelope | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HSE1 | YHL002W | Subunit of the endosomal Vps27p-Hse1p complex | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | BOI1 | YBL085W | Protein involved in polar growth, functionally redundant with Boi2p | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | MSD1 | YPL104W | Mitochondrial aspartyl-tRNA synthetase | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | BBC1 | YJL020C | Protein possibly involved in assembly of actin patches | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | FHL1 | YPR104C | Regulator of ribosomal protein (RP) transcription | physical | 1 | 1 | 1 | Affinity Capture-Western | 
            
                | MMS22 | YLR320W | Subunit of E3 ubiquitin ligase complex involved in replication repair | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | NBP2 | YDR162C | Protein involved in the HOG (high osmolarity glycerol) pathway | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | ELP3 | YPL086C | Subunit of Elongator complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPL4A | YBR031W | Ribosomal 60S subunit protein L4A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | PEX13 | YLR191W | Peroxisomal importomer complex component | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | RPS13 | YDR064W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS1A | YLR441C | Ribosomal protein of the small (40S) subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPA14 | YDR156W | RNA polymerase I subunit A14 | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | NMD2 | YHR077C | Protein involved in the nonsense-mediated mRNA decay (NMD) pathway | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CST9 | YLR394W | SUMO E3 ligase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | EMP46 | YLR080W | Integral membrane component of ER-derived COPII-coated vesicles | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | MPT5 | YGL178W | mRNA-binding protein of the PUF family | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | CLA4 | YNL298W | Cdc42p-activated signal transducing kinase | genetic | 1 | 1 | 1 | Dosage Growth Defect | 
            
                | RPL25 | YOL127W | Ribosomal 60S subunit protein L25 | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPL31A | YDL075W | Ribosomal 60S subunit protein L31A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS2 | YGL123W | Protein component of the small (40S) subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | DOM34 | YNL001W | Protein that facilitates ribosomal subunit dissociation | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPS20 | YHL015W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | PIN3 | YPR154W | Negative regulator of actin nucleation-promoting factor activity | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | MOG1 | YJR074W | Conserved nuclear protein that interacts with GTP-Gsp1p | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | RPS0A | YGR214W | Ribosomal 40S subunit protein S0A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS18A | YDR450W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | GIS2 | YNL255C | Translational activator for mRNAs with internal ribosome entry sites | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RPS6A | YPL090C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS9A | YPL081W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPL4B | YDR012W | Ribosomal 60S subunit protein L4B | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPL19A | YBR084C-A | Ribosomal 60S subunit protein L19A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPL26A | YLR344W | Ribosomal 60S subunit protein L26A | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS12 | YOR369C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS19A | YOL121C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS27B | YHR021C | Protein component of the small (40S) ribosomal subunit | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | RPS27A | YKL156W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPS27A | YKL156W | Protein component of the small (40S) ribosomal subunit | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | RPS15 | YOL040C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | CBT1 | YKL208W | Protein involved in 5' RNA end processing | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | DBR1 | YKL149C | RNA lariat debranching enzyme | genetic | 1 | 1 | 1 | Positive Genetic |