| MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure |
| PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Reconstituted Complex |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
7 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
physical |
7 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid |
| PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Two-hybrid, Two-hybrid |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect |
| MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
2 |
2 |
2 |
Two-hybrid, Biochemical Activity |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SMX2 |
YFL017W-A |
Core Sm protein Sm G |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
physical |
1 |
1 |
1 |
Co-purification |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAB1 |
YER165W |
Poly(A) binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VAC14 |
YLR386W |
Enzyme regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
| YCR101C |
YCR101C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| WHI4 |
YDL224C |
Putative RNA binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Two-hybrid |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Two-hybrid |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MRPL4 |
YLR439W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
1 |
1 |
1 |
Two-hybrid |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PIM1 |
YBL022C |
ATP-dependent Lon protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SME1 |
YOR159C |
Core Sm protein Sm E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FET4 |
YMR319C |
Low-affinity Fe(II) transporter of the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
physical |
1 |
1 |
1 |
Two-hybrid |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Two-hybrid |
| CBP3 |
YPL215W |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| DOG1 |
YHR044C |
2-deoxyglucose-6-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| MDJ1 |
YFL016C |
Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
physical |
1 |
1 |
1 |
Two-hybrid |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
physical |
1 |
1 |
1 |
Two-hybrid |
| NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Two-hybrid |
| FOB1 |
YDR110W |
Nucleolar protein that binds the rDNA replication fork barrier site |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| MSL5 |
YLR116W |
Component of commitment complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
physical |
1 |
1 |
1 |
Two-hybrid |
| OSW7 |
YFR039C |
Protein involved in outer spore wall assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
physical |
1 |
1 |
1 |
Two-hybrid |
| CRR1 |
YLR213C |
Putative glycoside hydrolase of the spore wall envelope |
physical |
1 |
1 |
1 |
Two-hybrid |
| ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| KIP1 |
YBL063W |
Kinesin-related motor protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| REV1 |
YOR346W |
Deoxycytidyl transferase |
physical |
1 |
1 |
1 |
Two-hybrid |