| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
| YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM2 |
YBR065C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MCO14 |
YHL018W |
Putative 4a-hydroxytetrahydrobiopterin dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RRN3 |
YKL125W |
Protein required for transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TOM40 |
YMR203W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TOM5 |
YPR133W-A |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR237C |
YGR237C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR131C |
YDR131C |
F-box protein subunit of SCF ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Positive Genetic |