Standard name Systematic name Name description Description
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p); phosphatidylethanolamine-binding protein (PEBP) family member and ortholog of hPEBP1/RKIP, a natural metastasis suppressor; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase; protein abundance increases in response to DNA replication stress
Visualize the interactome of TFS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.978 0.989 0.994
Cell Periphery NaN NaN 0.050

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1030

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TFS1 0 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
IRA2 YOL081W GTPase-activating protein physical 4 3 2 Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
PRC1 YMR297W Vacuolar carboxypeptidase Y (proteinase C, CPY) physical 3 2 3 Biochemical Activity, Reconstituted Complex, Reconstituted Complex
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 3 1 3 Dosage Rescue, Dosage Rescue, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
SET4 YJL105W Chromatin-associated protein involved in control of stress response regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, quantitative reverse transcription polymerase chain reaction evidence
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
PRO1 YDR300C Gamma-glutamyl kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
MAC1 YMR021C Copper-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RGM1 YMR182C Putative zinc finger DNA binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
FLO8 YER109C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase physical 1 1 1 Affinity Capture-MS
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex physical 1 1 1 Affinity Capture-MS
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Affinity Capture-MS
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
APE1 YKL103C Vacuolar aminopeptidase yscI physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Positive Genetic
ARF2 YDL137W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Rescue
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Positive Genetic
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-MS
HSP150 YJL159W O-mannosylated heat shock protein genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA physical 1 1 1 Affinity Capture-MS
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Positive Genetic
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
CIT1 YNR001C Mitochondrial citrate synthase physical 1 1 1 Affinity Capture-MS
HAM1 YJR069C Nucleoside triphosphate pyrophosphohydrolase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
FIG2 YCR089W Cell wall adhesin, expressed specifically during mating genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
CWH43 YCR017C GPI lipid remodelase genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions genetic 1 1 1 Positive Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
PFA4 YOL003C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Negative Genetic
COX13 YGL191W Subunit VIa of cytochrome c oxidase genetic 1 1 1 Negative Genetic
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Positive Genetic
YHR212W-A YHR212W-A Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
YIL152W YIL152W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic