Standard name Systematic name Name description Description
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes Subunit of the HOPS and the CORVET complexes; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages
Visualize the interactome of VPS16
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.399 0.300 0.472
Mito 0.444 0.489 0.283
Nuc Periphery 0.061 NaN NaN
Nucleolus 0.273 0.180 0.094
SpindlePole 0.136 NaN 0.319
Vac/Vac Memb 0.217 0.318 0.283

GFP localization & abundance

GFP localization GFP abundance
vacuolar membrane 1300

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VPS16 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes physical 14 5 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex physical 12 2 10 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 11 4 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
VAM7 YGL212W Vacuolar SNARE protein physical 9 2 8 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex physical 9 4 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
VPS8 YAL002W Membrane-binding component of the CORVET complex physical 7 2 6 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
PEP3 YLR148W Component of CORVET membrane tethering complex physical 7 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE physical 6 2 5 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
VPS3 YDR495C Component of CORVET membrane tethering complex physical 5 3 5 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
YPT7 YML001W Rab family GTPase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex physical 1 1 1 Reconstituted Complex
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Co-fractionation
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Lethality
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 1 1 1 Dosage Rescue
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Synthetic Growth Defect
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 1 1 1 Dosage Rescue
YPT52 YKR014C Endosomal Rab family GTPase physical 1 1 1 Two-hybrid
YPT52 YKR014C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform physical 1 1 1 Biochemical Activity
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Phenotypic Enhancement
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 1 1 1 Phenotypic Enhancement
YPT35 YHR105W Endosomal protein of unknown function genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
SES1 YDR023W Cytosolic seryl-tRNA synthetase genetic 1 1 1 Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
SEC4 YFL005W Rab family GTPase physical 1 1 1 Two-hybrid
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 PCA
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Phenotypic Enhancement
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Synthetic Growth Defect
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Phenotypic Enhancement
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance genetic 1 1 1 Phenotypic Suppression
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Synthetic Lethality
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Lethality
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Synthetic Lethality
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS