MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SRY1 |
YKL218C |
3-hydroxyaspartate dehydratase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM2 |
YBR065C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
PCA |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
PCA |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
1 |
1 |
1 |
PCA |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
PCA |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
PCA |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
1 |
1 |
1 |
PCA |
PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
physical |
1 |
1 |
1 |
PCA |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNS1 |
YJR131W |
Alpha-1,2-mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB4 |
YOL143C |
Lumazine synthase (DMRL synthase) |
physical |
1 |
1 |
1 |
Two-hybrid |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAG7 |
YOR134W |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
PCA |
CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
PCA |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
physical |
1 |
1 |
1 |
PCA |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
PCA |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPS12 |
YNR036C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
PCA |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM39 |
YOL053W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
1 |
1 |
1 |
PCA |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
physical |
1 |
1 |
1 |
PCA |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
physical |
1 |
1 |
1 |
PCA |
COS1 |
YNL336W |
Endosomal protein involved in turnover of plasma membrane proteins |
physical |
1 |
1 |
1 |
PCA |
COS8 |
YHL048W |
Endosomal protein involved in turnover of plasma membrane proteins |
physical |
1 |
1 |
1 |
PCA |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
1 |
1 |
1 |
PCA |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
physical |
1 |
1 |
1 |
PCA |
AAD10 |
YJR155W |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
physical |
1 |
1 |
1 |
PCA |
GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPS2 |
YLR168C |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
PCA |
AIM36 |
YMR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC2 |
YBR147W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL081W |
YGL081W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |